Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 5/20 | 0.35 |
| ▸ | NPC1 | O15118 | 5/20 | 0.35 |
| ▸ | RAB9A | P51151 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 5/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30622228 | 1.00 | TDP1 (0.36) | TDP1L3MBTL1LMNARXFP1MAPT | |
| SCHEMBL30622257 | 0.87 | BRD4 (0.36) | LMNASMN1; SMN2 | |
| SCHEMBL29133005 | 0.81 | HDAC6 (0.39) | — | |
| SCHEMBL30622220 | 0.81 | HDAC6 (0.39) | — | |
| SCHEMBL30622258 | 0.80 | ALDH1A1 (0.43) | L3MBTL1MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL29133060 | 0.80 | ALDH1A1 (0.43) | L3MBTL1MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL930734 | 0.75 | CA2 (0.45) | TDP1L3MBTL1LMNARXFP1MAPT | |
| SCHEMBL24921754 | 0.71 | BRD4 (0.38) | L3MBTL1MAPTHPGDNPC1RAB9A | |
| SCHEMBL29133064 | 0.71 | NOTUM (0.43) | L3MBTL1LMNARXFP1MAPTALDH1A1 | |
| SCHEMBL8280823 | 0.71 | MAPK1 (0.41) | L3MBTL1LMNARXFP1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117088884-A | Imidazopyridazine derivatives as GABAA receptor modulators, pharmaceutical compositions and uses | 上海赛默罗德生物科技有限公司 | 2023-11-21 | — | — | CN | disclosed |