SCHEMBL29133515

SCHEMBL29133515

O=[N+]([O-])c1ccc(-n2c3ccccc3c3ccccc32)c(C(F)(F)F)c1

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.50
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
LMNA P02545 2/20 0.47
POLB P06746 1/20 0.45
ATM Q13315 1/20 0.45
HTR7 P34969 2/20 0.41
PDE7A Q13946 1/20 0.41
ALDH1A1 P00352 5/20 0.41
MAPK1 P28482 2/20 0.41
HTT P42858 2/20 0.40
PKM P14618 1/20 0.40
SLC6A9 P48067 1/20 0.40
HTR1A P08908 1/20 0.40
IDO1 P14902 1/20 0.40
TDO2 P48775 1/20 0.40
IDO2 Q6ZQW0 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30697427 1.00 MAPT (0.50) MAPTMEN1KMT2ALMNAPOLB
SCHEMBL7515416 0.80 ALDH1A1 (0.57) MAPTMEN1KMT2ALMNAPOLB
SCHEMBL15460299 0.78 MAPT (0.54) MAPTMEN1KMT2ALMNAPOLB
SCHEMBL17810095 0.78 MAPT (0.54) MAPTMEN1KMT2ALMNAPOLB
SCHEMBL20282679 0.77 KDM4E (0.43) MAPTPOLBATMALDH1A1
SCHEMBL17950297 0.76 HCAR1 (0.39) MEN1KMT2AATMALDH1A1IDO1
SCHEMBL17950026 0.76 KIF11 (0.53) MAPTMEN1KMT2AATMALDH1A1
SCHEMBL28134313 0.76 ALDH1A1 (0.40) MAPTMEN1KMT2ALMNAPOLB
SCHEMBL29133516 0.75 GAA (0.46) MAPTMEN1KMT2ALMNAPOLB
SCHEMBL30704430 0.75 GAA (0.46) MAPTMEN1KMT2ALMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117327278-A Trifluoromethyl-terminated fluorinated polyamide imide polymer, preparation method thereof and application thereof in electrochromic film 南通际光光电科技有限公司 2024-01-02 CN claimed
CN-117327279-A Fluorinated polyamide imide polymer containing triphenylamine and carbazole units, preparation method thereof and application of fluorinated polyamide imide polymer in electrochromic film 南通际光光电科技有限公司 2024-01-02 CN claimed
CN-117327278-A Trifluoromethyl-terminated fluorinated polyamide imide polymer, preparation method thereof and application thereof in electrochromic film 南通际光光电科技有限公司 2024-01-02 CN disclosed
CN-117327279-A Fluorinated polyamide imide polymer containing triphenylamine and carbazole units, preparation method thereof and application of fluorinated polyamide imide polymer in electrochromic film 南通际光光电科技有限公司 2024-01-02 CN disclosed