SCHEMBL15460299

SCHEMBL15460299

O=[N+]([O-])c1ccc(-n2c3ccccc3c3ccccc32)c(Cl)c1

nearest known ligand 0.54

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.54
ALDH1A1 P00352 8/20 0.53
HPGD P15428 1/20 0.53
LMNA P02545 6/20 0.50
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
SMN1; SMN2 Q16637 3/20 0.50
MAPK1 P28482 2/20 0.50
HSD17B10 Q99714 1/20 0.50
POLB P06746 1/20 0.48
ATM Q13315 1/20 0.48
GAA P10253 3/20 0.47
PDE7A Q13946 1/20 0.46
P2RX4 Q99571 1/20 0.43
HTT P42858 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7515416 0.83 ALDH1A1 (0.57) MAPTALDH1A1HPGDLMNAMEN1
SCHEMBL17810095 0.82 MAPT (0.54) MAPTALDH1A1LMNAMEN1KMT2A
SCHEMBL4762936 0.80 ALDH1A1 (0.45) MAPTALDH1A1HPGDLMNAMEN1
SCHEMBL29133515 0.78 MAPT (0.50) MAPTALDH1A1LMNAMEN1KMT2A
SCHEMBL30697427 0.78 MAPT (0.50) MAPTALDH1A1LMNAMEN1KMT2A
SCHEMBL17810102 0.76 MAPT (0.51) MAPTALDH1A1LMNAMEN1KMT2A
SCHEMBL17810030 0.74 MAPT (0.52) MAPTALDH1A1LMNAMEN1KMT2A
SCHEMBL10913298 0.74 HSD17B10 (0.56) MAPTALDH1A1HPGDLMNAMEN1
SCHEMBL14422449 0.74 RORC (0.48) MAPTALDH1A1HPGDLMNAMEN1
SCHEMBL31548612 0.74 MAPT (0.68) MAPTALDH1A1LMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10720586-B2 Organic electroluminescent device; a charge transporting material for the organic electroluminescent device; and a luminescent device, a display device and a lighting system using the organic electroluminescent device UDC IRELAND LIMITED (IE) 2020-07-21 US disclosed
US-20180145264-A1 Organic Electroluminescent Device; A Charge Transporting Material For The Organic Electroluminescent Device; And A Luminescent Device, A Display Device And A Lighting System Using The Organic Electroluminescent Device UDC IRELAND LTD (IE) 2018-05-24 US disclosed
US-20180145264-A1 Organic Electroluminescent Device; A Charge Transporting Material For The Organic Electroluminescent Device; And A Luminescent Device, A Display Device And A Lighting System Using The Organic Electroluminescent Device UDC IRELAND LTD (IE) 2018-05-24 US disclosed
US-9887371-B2 Organic electroluminescent device; a charge transporting material for the organic electroluminescent device; and a luminescent device, a display device and a lighting system using the organic electroluminescent device UDC IRELAND LIMITED (IE) 2018-02-06 US disclosed
US-9887371-B2 Organic electroluminescent device; a charge transporting material for the organic electroluminescent device; and a luminescent device, a display device and a lighting system using the organic electroluminescent device UDC IRELAND LIMITED (IE) 2018-02-06 US disclosed
US-20160260910-A1 Organic Electroluminescent Device; A Charge Transporting Material For The Organic Electroluminescent Device; And A Luminescent Device, A Display Device And A Lighting System Using The Organic Electroluminescent Device UDC IRELAND LTD (IE) 2016-09-08 US disclosed
US-20160260910-A1 Organic Electroluminescent Device; A Charge Transporting Material For The Organic Electroluminescent Device; And A Luminescent Device, A Display Device And A Lighting System Using The Organic Electroluminescent Device UDC IRELAND LTD (IE) 2016-09-08 US disclosed
US-9306176-B2 Organic electroluminescent device; a charge transporting material for the organic electroluminescent device; and a luminescent device, a display device and a lighting system using the organic electroluminescent device UDC IRELAND LIMITED (IE) 2016-04-05 US disclosed
US-9306176-B2 Organic electroluminescent device; a charge transporting material for the organic electroluminescent device; and a luminescent device, a display device and a lighting system using the organic electroluminescent device UDC IRELAND LIMITED (IE) 2016-04-05 US disclosed
US-20140034914-A1 Organic Electroluminescent Device; A Charge Transporting Material For The Organic Electroluminescent Device; And A Luminescent Device, A Display Device And A Lighting System Using The Organic Electroluminescent Device UDC IRELAND LIMITED (IE) 2014-02-06 US disclosed
US-20140034914-A1 Organic Electroluminescent Device; A Charge Transporting Material For The Organic Electroluminescent Device; And A Luminescent Device, A Display Device And A Lighting System Using The Organic Electroluminescent Device UDC IRELAND LIMITED (IE) 2014-02-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180145264-A1 Organic Electroluminescent Device; A Charge Transporting Material For The Organic Electroluminescent Device; And A Luminescent Device, A Display Device And A Lighting System Using The Organic Electroluminescent Device SLC43A1, SLC6A19, AOC3 MAPT 2962/4885ALDH1A1 279/4885HPGD 3558/4885
US-10720586-B2 Organic electroluminescent device; a charge transporting material for the organic electroluminescent device; and a luminescent device, a display device and a lighting system using the organic electroluminescent device L1CAM, SLC19A2, RPS19 MAPT 1712/4885ALDH1A1 25/4885HPGD 4134/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.