Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 8/20 | 0.56 |
| ▸ | GART | P22102 | 5/20 | 0.56 |
| ▸ | TYMS | P04818 | 4/20 | 0.56 |
| ▸ | ATIC | P31939 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.56 |
| ▸ | TLR4 | O00206 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL338037 | 0.91 | DHFR (0.57) | DHFRGARTTYMSATICKDM4E | |
| SCHEMBL20486467 | 0.91 | DHFR (0.57) | DHFRGARTTYMSATICKDM4E | |
| SCHEMBL16583122 | 0.91 | DHFR (0.57) | DHFRGARTTYMSATICKDM4E | |
| SCHEMBL28135233 | 0.91 | DHFR (0.57) | DHFRGARTTYMSATICKDM4E | |
| SCHEMBL869876 | 0.91 | DHFR (0.57) | DHFRGARTTYMSATICKDM4E | |
| SCHEMBL25167471 | 0.91 | DHFR (0.57) | DHFRGARTTYMSATICKDM4E | |
| SCHEMBL28344641 | 0.91 | DHFR (0.57) | DHFRGARTTYMSATICKDM4E | |
| SCHEMBL3771709 | 0.90 | DHFR (0.56) | DHFRGARTTYMSATICKDM4E | |
| SCHEMBL15530423 | 0.90 | DHFR (0.56) | DHFRGARTTYMSATICKDM4E | |
| SCHEMBL29100467 | 0.90 | DHFR (0.56) | DHFRGARTTYMSATICKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117337190-A | Folate receptor targeted conjugates, compositions and delivery to the central nervous system | 普渡研究基金会 | 2024-01-02 | — | — | CN | disclosed |