Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CSF1R | P07333 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.40 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | F2R | P25116 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ACLY | P53396 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2908904 | 0.93 | KDR (0.46) | KDRKDM4EHTTCSF1RKMT2A | |
| SCHEMBL1496333 | 0.86 | KDR (0.46) | KDRKDM4EHTTCSF1RKMT2A | |
| SCHEMBL4018128 | 0.79 | KDR (0.58) | KDRKDM4EHTTKMT2AMEN1 | |
| SCHEMBL1496254 | 0.78 | KDR (0.48) | KDRKDM4EHTTKMT2AMEN1 | |
| SCHEMBL2914597 | 0.78 | LMNA (0.50) | KDRKDM4EHTTKMT2AMEN1 | |
| SCHEMBL2916664 | 0.78 | LMNA (0.49) | KDRKDM4EHTTKMT2AMEN1 | |
| SCHEMBL2909264 | 0.77 | LMNA (0.50) | KDRKDM4EHTTKMT2AMEN1 | |
| SCHEMBL4019331 | 0.76 | KDR (0.68) | KDRKDM4EHTTKMT2AMEN1 | |
| SCHEMBL1496284 | 0.76 | KDR (0.52) | KDRKMT2AMEN1NPC1GAA | |
| SCHEMBL1496291 | 0.76 | KDM4E (0.47) | KDRKDM4EHTTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1854787-B1 | NOVEL CYCLIC COMPOUND HAVING QUINOLYLALKYLTHIO GROUP | SANTEN PHARMACEUTICAL CO LTD (JP) | 2010-09-01 | — | — | EP | claimed |