SCHEMBL29134002

SCHEMBL29134002

CCCCC(OC(=O)/C=C\C(=O)OCC)N(C)C

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 5/20 0.44
ATM Q13315 2/20 0.44
TSHR P16473 2/20 0.39
MAPT P10636 5/20 0.38
RAB9A P51151 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
TDP1 Q9NUW8 2/20 0.35
ALDH1A1 P00352 2/20 0.35
CA1 P00915 3/20 0.34
CA2 P00918 3/20 0.34
CYP3A4 P08684 2/20 0.34
LMNA P02545 3/20 0.33
CA12 O43570 2/20 0.33
CA9 Q16790 2/20 0.33
MDM2 Q00987 2/20 0.33
CA7 P43166 1/20 0.33
CA14 Q9ULX7 1/20 0.33
MDM4 O15151 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL544701 0.87 ATM (0.41) HCAR2ATMTSHRMAPTCA1
SCHEMBL543768 0.87 ATM (0.41) HCAR2ATMTSHRMAPTCA1
SCHEMBL5247453 0.79 TSHR (0.49) ATMTSHRALDH1A1CA1CA2
SCHEMBL28669002 0.78 ALDH1A1 (0.39) TSHRALDH1A1CA1CA2LMNA
SCHEMBL27813968 0.78 HCAR2 (0.47) HCAR2ATMTSHRMAPTRAB9A
SCHEMBL27899121 0.78 HCAR2 (0.47) HCAR2ATMTSHRMAPTRAB9A
SCHEMBL499273 0.74 TSHR (0.44) TSHRMAPTCA1
SCHEMBL11673372 0.73 TSHR (0.43) TSHRMAPTALDH1A1CYP3A4LMNA
SCHEMBL499540 0.73 TSHR (0.43) TSHRMAPTALDH1A1CYP3A4LMNA
SCHEMBL499747 0.73 TSHR (0.43) TSHRMAPTALDH1A1CYP3A4LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116836082-A High-adhesion polyaspartic acid ester resin and preparation method and application thereof 深圳市宝安区新材料研究院 2023-10-03 CN disclosed