Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.41 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 3/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1801222 | 0.83 | CYP3A4 (0.48) | ALDH1A1ALOX15HSD17B10TSHRCYP3A4 | |
| SCHEMBL525507 | 0.81 | ALDH1A1 (0.48) | ALDH1A1ALOX15HSD17B10TSHRCYP3A4 | |
| SCHEMBL126200 | 0.79 | ALDH1A1 (0.43) | ALDH1A1ALOX15HSD17B10TSHRCYP3A4 | |
| SCHEMBL29631738 | 0.79 | ALDH1A1 (0.43) | ALDH1A1ALOX15HSD17B10TSHRCYP3A4 | |
| SCHEMBL1568810 | 0.79 | ALDH1A1 (0.52) | ALDH1A1ALOX15HSD17B10TSHRCYP3A4 | |
| SCHEMBL315655 | 0.79 | ALDH1A1 (0.46) | ALDH1A1ALOX15HSD17B10TSHRCYP3A4 | |
| SCHEMBL6538658 | 0.79 | CYP3A4 (0.43) | ALDH1A1ALOX15HSD17B10TSHRCYP3A4 | |
| Hydrochloric Acid SCHEMBL5204358 | 0.79 | ALDH1A1 (0.46) | ALDH1A1ALOX15HSD17B10TSHRCYP3A4 | |
| SCHEMBL31290749 | 0.77 | TRPA1 (0.46) | ALDH1A1ALOX15HSD17B10ESR1ESR2 | |
| SCHEMBL3708636 | 0.77 | TRPA1 (0.46) | ALDH1A1ALOX15HSD17B10ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1129689-B1 | Keratinous fiber dyeing composition comprising N-(2-hydroxybenzene)-carbamate or N-(2-hydroxybenzene)urea derivatives as coupling agents and process for dyeing | OREAL (FR) | 2008-07-09 | — | — | EP | claimed |
| EP-1064268-B1 | NOVEL CATIONIC COMPOUNDS, THEIR USE AS COUPLING AGENTS FOR OXIDATION DYEING OF KERATINOUS FIBRES, DYEING COMPOSITIONS AND DYEING METHODS | OREAL (FR) | 2005-11-30 | — | — | EP | claimed |
| US-20040083557-A1 | Permanent coloring of hair using carbonate salts and bicarbonate salts and using percarbamic acid precursors | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. | 2004-05-06 | — | — | US | claimed |
| EP-1139990-A1 | AGENT FOR DYING KERATIN FIBERS | Henkel Kommanditgesellschaft auf Aktien (DE) | 2001-10-10 | — | — | EP | claimed |
| WO-2000038635-A1 | AGENT FOR DYING KERATIN FIBERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2000-07-06 | — | — | WO | claimed |
| EP-0580713-A1 | METHOD FOR DYEING KERATIN FIBRES WITH AMINOINDOLES HAVING ALKALINE pH, AND COMPOSITIONS THEREFOR. | OREAL (FR) | 1994-02-02 | — | — | EP | claimed |
| WO-1992018093-A1 | METHOD FOR DYEING KERATIN FIBRES WITH AMINOINDOLES HAVING ALKALINE pH, AND COMPOSITIONS THEREFOR | L'OREAL (FR) | 1992-10-29 | — | — | WO | claimed |
| EP-0428441-A2 | Keratinic fibre dyeing compostions containing oxydation dye precursors and derivatives of 4-hydroxyindole as couplers, and dyeing process using same | L'OREAL (FR) | 1991-05-22 | — | — | EP | claimed |
| EP-0428442-A1 | Composition comprising derivatives of 6- or 7-hydroxyindole as couplers and dyeing processes using same | L'OREAL (FR) | 1991-05-22 | — | — | EP | claimed |
| US-11273115-B2 | Hair dyeing method using a dye composition and an oxidizing composition, said compositions comprising a scleroglucan gum | L'OREAL (FR) | 2022-03-15 | — | — | US | disclosed |
| US-20210113449-A1 | HAIR DYEING METHOD USING A DYE COMPOSITION AND AN OXIDIZING COMPOSITION, SAID COMPOSITIONS COMPRISING A SCLEROGLUCAN GUM | L'OREAL (FR) | 2021-04-22 | — | — | US | disclosed |
| CN-110368906-A | The preparation method of the adsorbent of adsorption uranium | 中核第四研究设计工程有限公司 | 2019-10-25 | — | — | CN | disclosed |
| EP-2552381-B1 | HAIR TREATMENT PROCESS USING A DIRECT EMULSION COMPRISING AN OXIDIZING AGENT AND A DIRECT EMULSION CONTAINING AN ALKALINE AGENT | OREAL (FR) | 2018-09-05 | — | — | EP | disclosed |
| EP-2427173-B1 | SCALP SOOTHING HAIR DYEING/PERMING AGENTS COMPRISING EXTRACT OF BOERHAVIA | HENKEL AG & CO KGAA (DE) | 2017-10-18 | — | — | EP | disclosed |
| EP-0591373-B1 | META-AMINOPHENOLS, THEIR USE AS COUPLERS FOR OXIDATION DYEING OF KERATINOUS FIBRES, DYE COMPOSITIONS AND METHOD | OREAL (FR) | 1996-05-22 | — | — | EP | disclosed |
| EP-0424261-B1 | Dyeing composition containing oxidation dyes precursors and aminoindole derivatives as coupling agent | OREAL (FR) | 1996-01-03 | — | — | EP | disclosed |
| EP-0591373-A1 | META-AMINOPHENOLS, THEIR USE AS COUPLERS FOR OXIDATION DYEING OF KERATINOUS FIBRES, DYE COMPOSITIONS AND METHOD. | OREAL (FR) | 1994-04-13 | — | — | EP | disclosed |
| WO-1993000066-A1 | META-AMINOPHENOLS, THEIR USE AS COUPLERS FOR OXIDATION DYEING OF KERATINOUS FIBRES, DYE COMPOSITIONS AND METHOD | L'OREAL (FR) | 1993-01-07 | — | — | WO | disclosed |
| EP-0424261-A1 | Dyeing composition containing oxidation dyes precursors and aminoindole derivatives as coupling agent | L'OREAL (FR) | 1991-04-24 | — | — | EP | disclosed |
| EP-0395837-A1 | Oxidation hair dyes based on 4-aminophenol derivatives as well as new 4-aminophenol derivatives | Wella Aktiengesellschaft (DE) | 1990-11-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11273115-B2 | Hair dyeing method using a dye composition and an oxidizing composition, said compositions comprising a scleroglucan gum | OGG1, ALPG, KRT18 | ALDH1A1 487/4885ALOX15 1876/4885HSD17B10 286/4885 |
| US-20210113449-A1 | HAIR DYEING METHOD USING A DYE COMPOSITION AND AN OXIDIZING COMPOSITION, SAID COMPOSITIONS COMPRISING A SCLEROGLUCAN GUM | OGG1, ALPG, KRT18 | ALDH1A1 487/4885ALOX15 1876/4885HSD17B10 286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.