SCHEMBL315655

SCHEMBL315655

Cc1c(O)ccc(N)c1O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.46
ALOX15 P16050 4/20 0.46
HSD17B10 Q99714 3/20 0.46
HDAC3 O15379 1/20 0.41
IDO1 P14902 1/20 0.41
EP300 Q09472 1/20 0.41
KAT2B Q92831 1/20 0.41
KAT8 Q9H7Z6 1/20 0.41
NCOR2 Q9Y618 1/20 0.41
PDE10A Q9Y233 1/20 0.41
ESR1 P03372 3/20 0.41
ESR2 Q92731 2/20 0.41
TYR P14679 1/20 0.39
CSNK2A2 P19784 1/20 0.39
CSNK2B P67870 1/20 0.39
CSNK2A1 P68400 1/20 0.39
CSNK2A3 Q8NEV1 1/20 0.39
CYP3A4 P08684 2/20 0.39
TRPA1 O75762 1/20 0.39
ATM Q13315 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1801222 0.83 CYP3A4 (0.48) ALDH1A1ALOX15HSD17B10HDAC3IDO1
SCHEMBL525507 0.81 ALDH1A1 (0.48) ALDH1A1ALOX15HSD17B10HDAC3IDO1
SCHEMBL30600212 0.79 ALDH1A1 (0.41) ALDH1A1ALOX15HSD17B10PDE10ACYP3A4
SCHEMBL4603633 0.79 ALOX15 (0.46) ALDH1A1ALOX15HSD17B10HDAC3IDO1
SCHEMBL16429372 0.79 POLB (0.44) ALDH1A1ALOX15HSD17B10HDAC3IDO1
SCHEMBL2795922 0.79 ALDH1A1 (0.41) ALDH1A1ALOX15HSD17B10PDE10ACYP3A4
Hydrochloric Acid SCHEMBL5204358 0.79 ALDH1A1 (0.46) ALDH1A1ALOX15HSD17B10HDAC3IDO1
SCHEMBL291343 0.79 ALDH1A1 (0.46) ALDH1A1ALOX15HSD17B10HDAC3IDO1
SCHEMBL31290749 0.77 TRPA1 (0.46) ALDH1A1ALOX15HSD17B10ESR1ESR2
SCHEMBL3708636 0.77 TRPA1 (0.46) ALDH1A1ALOX15HSD17B10ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 212 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101091691-B Keratin fibre dyeing composition containing 2, 3-diamino-6, 7-dihydro-1H, 5H-pyrazolo [1,2-a ] pyrazol-1-one, 6-chloro-2-methyl-5-aminophenol and substituted meta-aminophenol OREAL 2012-05-02 CN claimed
CN-100528126-C Composition comprising at least one coupler chosen from 2-chloro-6-methyl-3-aminophenol and addition salts thereof, at least one oxidation base, and at least one associative polymer comprising at leas OREAL (FR) 2009-08-19 CN claimed
EP-1129689-B1 Keratinous fiber dyeing composition comprising N-(2-hydroxybenzene)-carbamate or N-(2-hydroxybenzene)urea derivatives as coupling agents and process for dyeing OREAL (FR) 2008-07-09 EP claimed
CN-101091691-A Composition for dyeing keratin fibres comprising 2,3-diamino-6,7-dihydro-1h,5h-pyrazolo[1,2-a]pyrazol-1-one, 6-chloro 2-methyl 5-aminophenol and a substituted meta-aminophenol OREAL (FR) 2007-12-26 CN claimed
CN-1882307-A Method for dyeing fibres containing keratine HENKEL KGAA (DE) 2006-12-20 CN claimed
EP-1064268-B1 NOVEL CATIONIC COMPOUNDS, THEIR USE AS COUPLING AGENTS FOR OXIDATION DYEING OF KERATINOUS FIBRES, DYEING COMPOSITIONS AND DYEING METHODS OREAL (FR) 2005-11-30 EP claimed
CN-1210012-C Composition for oxidation dyeing keratoprotein fibre and method for dyeing using said composition OREAL (FR) 2005-07-13 CN claimed
CN-1201717-C Composite for oxidation-dyeing keratin fibre and its dyeing method OREAL (FR) 2005-05-18 CN claimed
CN-1200682-C Keratin-fiber oxidation dyeing composition and dyeing method using same OREAL (FR) 2005-05-11 CN claimed
CN-1602836-A Dye composition comprising at least one oxidation base, 2-chloro-6-methyl-3-aminophenol and 3-methyl-1-phenyl-5-pyrazolone OREAL (FR) 2005-04-06 CN claimed
CN-1258213-A Composition for the oxidation dyeing of keratin fibres comprising a 3-aminopyridinazo derivative and dyeing process using this composition OREAL (FR) 2000-06-28 CN claimed
CN-1248577-A Novel cation type 4-oxyindole, its oxidation dyeing, dyeing composition and dyeing method for keration fibre OREAL (FR) 2000-03-29 CN claimed
CN-1241136-A Oxidation dye composition for keratin fibres OREAL (FR) 2000-01-12 CN claimed
CN-1241138-A Oxidation dyeing composition for keratin fibres and dyeing method using said composition OREAL (FR) 2000-01-12 CN claimed
CN-1241135-A Oxidation dyeing composition for keratin fibres OREAL (FR) 2000-01-12 CN claimed
CN-1241137-A Composition for the oxidation dyeing of keratin fibres and dyeing process using this composition OREAL (FR) 2000-01-12 CN claimed
CN-1236609-A Oxidation dyeing composition of keration fibre and dyeing method using same OREAL (FR) 1999-12-01 CN claimed
CN-1189332-A Composition for oxidation dyeing of keratin fibres and dyeing process using this composition OREAL (FR) 1998-08-05 CN claimed
CN-1189333-A Composition for oxidation dyeing of keratin fibres and dyeing process using this composition OREAL (FR) 1998-08-05 CN claimed
CN-1137375-A Composition for oxidation dyeing of keratin fibres, comprising at least two oxidation bases and dation be coupler, and dyeing process OREAL (FR) 1996-12-11 CN claimed