Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1530500 | 0.74 | GRIA2 (0.44) | CA1CA2CA9 | |
| SCHEMBL22439483 | 0.71 | TGM2 (0.40) | — | |
| SCHEMBL24698411 | 0.71 | AAK1 (0.38) | — | |
| SCHEMBL30015258 | 0.71 | AAK1 (0.38) | — | |
| SCHEMBL2589648 | 0.70 | VEGFA (0.39) | CA1CA2CA9 | |
| SCHEMBL22438912 | 0.70 | KDM1A (0.39) | CA1CA2CA9 | |
| SCHEMBL29134322 | 0.68 | ADRA2A (0.42) | CA2 | |
| SCHEMBL29134339 | 0.67 | SRD5A1 (0.32) | SLC22A12 | |
| SCHEMBL30014797 | 0.67 | SRD5A1 (0.32) | SLC22A12 | |
| SCHEMBL8160279 | 0.65 | GRIA2 (0.44) | CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4313967-A1 | KHK INHIBITORS | GILEAD SCIENCES, INC. (US) | 2024-02-07 | — | — | EP | disclosed |
| CN-117120429-A | KHK inhibitor | 吉利德科学公司 | 2023-11-24 | — | — | CN | disclosed |
| WO-2022212194-A1 | KHK INHIBITORS | GILEAD SCIENCES, INC. (US) | 2022-10-06 | — | — | WO | disclosed |