Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 6/20 | 0.73 |
| ▸ | ALPL | P05186 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | WDR5 | P61964 | 3/20 | 0.52 |
| ▸ | MYC | P01106 | 1/20 | 0.52 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.52 |
| ▸ | BRD4 | O60885 | 2/20 | 0.50 |
| ▸ | BRD2 | P25440 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29134937 | 0.90 | SLC22A12 (0.58) | SLC22A12ALPLSMN1; SMN2WDR5MYC | |
| SCHEMBL29134947 | 0.82 | ALPL (0.58) | ALPLSMN1; SMN2TRIM24BRD4BRD2 | |
| SCHEMBL329987 | 0.78 | TP53 (0.73) | ALPLSMN1; SMN2WDR5MYCKMT2A | |
| SCHEMBL18530464 | 0.76 | ALPL (0.70) | ALPLSMN1; SMN2HPGDMEN1ALDH1A1 | |
| SCHEMBL21761109 | 0.75 | LMNA (0.73) | ALPLSMN1; SMN2HPGDMEN1ALDH1A1 | |
| SCHEMBL21760616 | 0.75 | ALPL (0.62) | ALPLSMN1; SMN2WDR5MYCTRIM24 | |
| SCHEMBL3761698 | 0.75 | ALPL (0.72) | ALPLSMN1; SMN2WDR5MEN1LMNA | |
| SCHEMBL14018775 | 0.73 | ALPL (0.59) | ALPLSMN1; SMN2WDR5MYCBRD4 | |
| SCHEMBL4650569 | 0.73 | SLC22A12 (0.73) | SLC22A12MEN1LMNAMAPTKMT2A | |
| SCHEMBL21761107 | 0.72 | ALPL (0.65) | ALPLSMN1; SMN2WDR5MYCBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117120429-A | KHK inhibitor | 吉利德科学公司 | 2023-11-24 | — | — | CN | disclosed |