Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.58 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.57 |
| ▸ | ALPL | P05186 | 6/20 | 0.56 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | BRD4 | O60885 | 2/20 | 0.53 |
| ▸ | BRD2 | P25440 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | WDR5 | P61964 | 2/20 | 0.49 |
| ▸ | EDNRB | P24530 | 2/20 | 0.49 |
| ▸ | EDNRA | P25101 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | MYC | P01106 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29134425 | 0.90 | SLC22A12 (0.73) | SLC22A12TRIM24ALPLSHMT2SMN1; SMN2 | |
| SCHEMBL29134947 | 0.85 | ALPL (0.58) | TRIM24ALPLSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL18530464 | 0.79 | ALPL (0.70) | ALPLSMN1; SMN2KMT2AMEN1GLA | |
| SCHEMBL21761109 | 0.78 | LMNA (0.73) | ALPLSMN1; SMN2KMT2AMEN1GLA | |
| SCHEMBL21760616 | 0.78 | ALPL (0.62) | TRIM24ALPLSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL3761698 | 0.78 | ALPL (0.72) | ALPLSMN1; SMN2KMT2AMEN1GLA | |
| SCHEMBL14018775 | 0.76 | ALPL (0.59) | ALPLSMN1; SMN2KMT2ABRD4BRD2 | |
| SCHEMBL329987 | 0.76 | TP53 (0.73) | ALPLSMN1; SMN2KMT2AGLAWDR5 | |
| SCHEMBL21761107 | 0.75 | ALPL (0.65) | ALPLSMN1; SMN2KMT2AMEN1BRD4 | |
| SCHEMBL286644 | 0.75 | AR (0.53) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117120429-A | KHK inhibitor | 吉利德科学公司 | 2023-11-24 | — | — | CN | disclosed |