Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 11/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.53 |
| ▸ | BRD4 | O60885 | 2/20 | 0.52 |
| ▸ | BRD2 | P25440 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12368216 | 0.86 | ALPL (0.72) | ALPLMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL29134937 | 0.85 | SLC22A12 (0.58) | ALPLMEN1KMT2ASMN1; SMN2GLA | |
| SCHEMBL15211896 | 0.85 | ALPL (0.82) | ALPL | |
| SCHEMBL18530464 | 0.84 | ALPL (0.70) | ALPLMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL21760616 | 0.83 | ALPL (0.62) | ALPLMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL21761109 | 0.83 | LMNA (0.73) | ALPLMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3761698 | 0.82 | ALPL (0.72) | ALPLMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL29134425 | 0.82 | SLC22A12 (0.73) | ALPLMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL14018775 | 0.81 | ALPL (0.59) | ALPLMAPTKMT2ASMN1; SMN2GLA | |
| SCHEMBL5962533 | 0.79 | SMN1; SMN2 (0.71) | ALPLMAPTMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117120429-A | KHK inhibitor | 吉利德科学公司 | 2023-11-24 | — | — | CN | disclosed |