Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28390646 | 0.82 | PLAUR (0.48) | KDM4EALDH1A1GAASMN1; SMN2HPGD | |
| SCHEMBL16596825 | 0.80 | ALDH1A1 (0.44) | KDM4EALDH1A1GAASMN1; SMN2DPP4 | |
| SCHEMBL29387435 | 0.79 | SMN1; SMN2 (0.43) | KDM4EALDH1A1GAASMN1; SMN2HPGD | |
| SCHEMBL4865308 | 0.79 | SMN1; SMN2 (0.43) | KDM4EALDH1A1GAASMN1; SMN2HPGD | |
| SCHEMBL29134590 | 0.75 | CYP17A1 (0.41) | KDM4EALDH1A1SMN1; SMN2HPGDMAPK14 | |
| SCHEMBL19309749 | 0.75 | ALKBH5 (0.51) | KDM4EALDH1A1GAASMN1; SMN2HPGD | |
| SCHEMBL28663530 | 0.73 | PTK2 (0.51) | KDM4EALDH1A1GAASMN1; SMN2MAPT | |
| SCHEMBL29134581 | 0.73 | MAPK14 (0.40) | KDM4EALDH1A1SMN1; SMN2HPGDMAPK14 | |
| SCHEMBL30704300 | 0.73 | MAPK14 (0.40) | KDM4EALDH1A1SMN1; SMN2HPGDMAPK14 | |
| SCHEMBL16596829 | 0.72 | ALDH1A1 (0.43) | KDM4EALDH1A1GAASMN1; SMN2DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117343044-A | Synthesis method of 2-methyl-1- (pyridine-2-yl) indole compound | 太原理工大学 | 2024-01-05 | — | — | CN | disclosed |