Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 3/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | VCP | P55072 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.37 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.35 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | PRKACA | P17612 | 1/20 | 0.35 |
| ▸ | LTK | P29376 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30704292 | 1.00 | CDC7 (0.39) | CDC7CYP11B2CYP11B1KDM4EALDH1A1 | |
| SCHEMBL28484200 | 0.80 | ALDH1A1 (0.44) | KDM4EALDH1A1L3MBTL1MAPT | |
| SCHEMBL28486433 | 0.77 | PDE2A (0.36) | CYP11B2CYP11B1KDM4EALDH1A1MAPT | |
| SCHEMBL28492642 | 0.76 | SLC6A2 (0.45) | KDM4EALDH1A1VCPNOTUMMAPT | |
| SCHEMBL28479875 | 0.74 | DDB1 (0.37) | CDC7CYP11B2CYP11B1KDM4EALDH1A1 | |
| SCHEMBL28562388 | 0.73 | CDC7 (0.60) | CDC7CYP11B2CYP11B1KDM4EALDH1A1 | |
| SCHEMBL10053515 | 0.73 | BRPF1 (0.45) | CDC7KDM4EALDH1A1GAAMAPT | |
| SCHEMBL29134576 | 0.72 | HSD17B10 (0.47) | KDM4EALDH1A1L3MBTL1GAAMAPT | |
| SCHEMBL16720818 | 0.70 | PDE4B (0.44) | KDM4EALDH1A1L3MBTL1MAPTGRM5 | |
| SCHEMBL22939250 | 0.69 | DHFR (0.38) | CDC7CYP11B2CYP11B1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117343044-A | Synthesis method of 2-methyl-1- (pyridine-2-yl) indole compound | 太原理工大学 | 2024-01-05 | — | — | CN | disclosed |