SCHEMBL29135

SCHEMBL29135

NC(=O)c1ccc2c(C(N)=O)c1-c1ccccc1-2

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 1/20 0.55
NFE2L2 Q16236 1/20 0.55
BCAT2 O15382 1/20 0.47
MAPT P10636 3/20 0.42
ALDH1A1 P00352 3/20 0.42
TSHR P16473 2/20 0.42
HSD17B10 Q99714 2/20 0.42
KDM4E B2RXH2 2/20 0.42
HPGD P15428 1/20 0.42
PDK2 Q15119 2/20 0.41
CSNK1A1 P48729 1/20 0.41
TYRO3 Q06418 1/20 0.41
DYRK1B Q9Y463 1/20 0.41
GRK6 P43250 1/20 0.41
BTK Q06187 1/20 0.41
KMT2A Q03164 2/20 0.40
ATM Q13315 1/20 0.40
METAP2 P50579 1/20 0.39
POLB P06746 2/20 0.39
RECQL P46063 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL278425 0.86 KEAP1 (0.49) KEAP1NFE2L2BCAT2MAPTALDH1A1
SCHEMBL41435 0.85 KEAP1 (0.64) KEAP1NFE2L2BCAT2MAPTALDH1A1
SCHEMBL4143761 0.79 BCAT2 (0.56) KEAP1NFE2L2BCAT2MAPTALDH1A1
SCHEMBL21081897 0.79 MAPT (0.47) KEAP1NFE2L2BCAT2MAPTALDH1A1
SCHEMBL3605803 0.79 KEAP1 (0.75) KEAP1NFE2L2BCAT2MAPTALDH1A1
SCHEMBL15798173 0.78 BRD4 (0.52) MAPTKMT2AMEN1BRD4
SCHEMBL3661535 0.76 BCAT2 (0.42) KEAP1NFE2L2BCAT2MAPTALDH1A1
SCHEMBL29438199 0.76 BCAT2 (0.42) KEAP1NFE2L2BCAT2MAPTALDH1A1
SCHEMBL10500642 0.74 KEAP1 (0.62) KEAP1NFE2L2MAPTALDH1A1TSHR
SCHEMBL16684995 0.73 BTK (0.53) KEAP1NFE2L2BCAT2MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 232 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021045850-A2 PHASE-INVERSION POLYMER COMPOSITE MATERIAL, FABRICATING METHODS AND APPLICATIONS OF SAME NORTHWESTERN UNIVERSITY (US) 2021-03-11 WO claimed
EP-3703922-A1 THERMOPLASTIC MATERIAL Chianese, Umberto (IT) 2020-09-09 EP claimed
EP-3500623-A1 POLYMER MATERIAL COMPRISING AT LEAST ONE DIFFERENT DOPING ELEMENT, USES AND PRODUCTION METHOD S-Techs GmbH (DE) 2019-06-26 EP claimed
WO-2018036607-A1 POLYMER MATERIAL COMPRISING AT LEAST ONE DIFFERENT DOPING ELEMENT, USES AND PRODUCTION METHOD S-TECHS GMBH (DE) 2018-03-01 WO claimed
EP-2716432-B1 Method of cleaving an adhesive joint 3M INNOVATIVE PROPERTIES CO (US) 2015-08-19 EP claimed
EP-2776508-A1 FLAME RETARDANT POLYAMIDE COMPOSITIONS FRX Polymers, Inc. (US) 2014-09-17 EP claimed
WO-2013071230-A1 FLAME RETARDANT POLYAMIDE COMPOSITIONS FRX POLYMERS, INC. (US) 2013-05-16 WO claimed
WO-2012025695-A1 BRACKET FOR DISPLAY DEVICES FOR AN AIRCRAFT COCKPIT AIRBUS OPERATIONS (FR) 2012-03-01 WO claimed
WO-2011075406-A1 FLAME, HEAT AND ELECTRIC ARC PROTECTIVE YARN AND FABRIC INTERNATIONAL GLOBAL TRADING USA, INC. (US) 2011-06-23 WO claimed
EP-2286020-A2 METHOD OF DYEING HIGH PERFORMANCE FABRICS Ten Cate Protect B.V. (NL) 2011-02-23 EP claimed
WO-2009098316-A2 METHOD OF DYEING HIGH PERFORMANCE FABRICS TEN CATE PROTECT B.V. (NL) 2009-08-13 WO claimed
US-6840967-B1 Dye diffusion promoting agents for aramids SOUTHERN MILLS, INC. (US) 2005-01-11 US claimed
EP-0924239-B1 Durable hydrophilic coating for textiles GEN ELECTRIC (US) 2004-11-24 EP claimed
EP-0947890-B1 Fabric fuser film XEROX CORP (US) 2004-05-12 EP claimed
EP-0331375-B1 Optical elements for radiation comprising graphite films MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) 1995-08-23 EP claimed
US-5042059-A Used in optical instruments for x-rays spectroscopes or microscopes, lenses and monochromators MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1991-08-20 US claimed
EP-0331375-A2 Optical elements for radiation comprising graphite films MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1989-09-06 EP claimed
EP-0330163-A2 Flame resistant staple fiber blend TEIJIN LIMITED (JP) 1989-08-30 EP claimed
EP-0285338-A2 Fire retardant structural textile panel GATES FORMED-FIBRE PRODUCTS INC. (US) 1988-10-05 EP claimed
US-4024308-A Durably flame proofed textile materials HOOKER CHEMICALS & PLASTICS CORPORATION (US) 1977-05-17 US claimed