SCHEMBL41435

SCHEMBL41435

NC(=O)c1ccc(C(N)=O)c2c1-c1ccccc1-2

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 1/20 0.64
NFE2L2 Q16236 1/20 0.64
BCAT2 O15382 1/20 0.56
ALDH1A1 P00352 3/20 0.50
MAPT P10636 2/20 0.50
TSHR P16473 2/20 0.50
HSD17B10 Q99714 2/20 0.50
KDM4E B2RXH2 2/20 0.50
HPGD P15428 1/20 0.50
PDK2 Q15119 2/20 0.47
GRK6 P43250 1/20 0.47
ATM Q13315 2/20 0.47
KMT2A Q03164 1/20 0.47
METAP2 P50579 1/20 0.46
POLB P06746 1/20 0.44
CYP3A4 P08684 1/20 0.44
PARP1 P09874 1/20 0.44
CYP2C19 P33261 1/20 0.44
RECQL P46063 1/20 0.44
BLM P54132 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16684995 0.87 BTK (0.53) KEAP1NFE2L2BCAT2ALDH1A1MAPT
SCHEMBL29135 0.85 KEAP1 (0.55) KEAP1NFE2L2BCAT2ALDH1A1MAPT
SCHEMBL5713285 0.85 KEAP1 (0.50) KEAP1NFE2L2BCAT2ALDH1A1MAPT
SCHEMBL28702676 0.84 KEAP1 (0.50) KEAP1NFE2L2BCAT2ALDH1A1MAPT
SCHEMBL3605803 0.84 KEAP1 (0.75) KEAP1NFE2L2BCAT2ALDH1A1MAPT
SCHEMBL17292717 0.83 KEAP1 (0.53) KEAP1NFE2L2BCAT2ALDH1A1MAPT
SCHEMBL8215227 0.83 KEAP1 (0.49) KEAP1NFE2L2BCAT2ALDH1A1MAPT
SCHEMBL1512156 0.81 KEAP1 (0.65) KEAP1NFE2L2BCAT2ALDH1A1MAPT
SCHEMBL7052546 0.80 KEAP1 (0.46) KEAP1NFE2L2BCAT2MAPTTSHR
SCHEMBL210767 0.79 BCAT2 (0.74) KEAP1NFE2L2BCAT2ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 732 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4370737-A1 DUPLEX CORD FOR USE AS A REINFORCEMENT IN A BELT BANDAGE OF A PNEUMATIC VEHICLE TYRE Continental Reifen Deutschland GmbH (DE) 2024-05-22 EP claimed
EP-4294910-A1 IMMORTALIZED CELL LINE FOR ENGINEERED SYNTHETIC LEATHER VitroLabs Inc (US) 2023-12-27 EP claimed
EP-4256162-A1 PROTECTIVE DEVICE FOR AN ELEMENT TO BE SECURED Ramseyer, Frédéric (CH) 2023-10-11 EP claimed
US-11779681-B2 Macroscopically alignable, injectable, soft hydrogel composition DWI—LEIBNIZ-INSTITUT FÜR INTERAKTIVE MATERIALIEN E.V. (DE) 2023-10-10 US claimed
WO-2023003254-A1 AGED-SKIN MODEL AND PRODUCTION METHOD THEREFOR 한림대학교 산학협력단 2023-01-26 WO claimed
WO-2023284924-A1 DUPLEX CORD FOR USE AS A REINFORCEMENT IN A BELT BANDAGE OF A PNEUMATIC VEHICLE TYRE CONTINENTAL REIFEN DEUTSCHLAND GMBH (DE) 2023-01-19 WO claimed
CN-114784223-A Positive plate and preparation method and application thereof 广东马车动力科技有限公司 2022-07-22 CN claimed
WO-2022122191-A1 PROTECTIVE DEVICE FOR AN ELEMENT TO BE SECURED RAMSEYER FREDERIC (CH) 2022-06-16 WO claimed
US-20210308331-A1 MACROSCOPICALLY ALIGNABLE, INJECTABLE, SOFT HYDROGEL COMPOSITION DWI - LEIBNIZ-INSTITUT FÜR INTERAKTIVE MATERIALIEN E.V. (DE) 2021-10-07 US claimed
US-11071806-B2 Macroscopically alignable, injectable, soft hydrogel composition DWI—LEIBNIZ-INSTITUT FÜR INTERAKTIVE MATERIALIEN E.V. (DE) 2021-07-27 US claimed
WO-2001096695-A1 COMPOSITE MEMBRANE FOR CONTROL OF INTERIOR ENVIRONMENTS SAINT-GOBAIN PERFORMANCE PLASTICS CORPORATION (US) 2001-12-20 WO claimed
WO-2001051767-A2 ADDITION OF SOLIDS TO GENERATE VISCOSITY DOWNHOLE SCHLUMBERGER TECHNOLOGY CORPORATION (US) 2001-07-19 WO claimed
WO-2001034377-A1 FIRE AND HEAT PROTECTION WRAPPING SYSTEM NO FIRE TECHNOLOGIES, INC. (US) 2001-05-17 WO claimed
EP-0612265-B1 FILTER BAG FOR HOT GASES DU PONT (US) 1996-05-01 EP claimed
EP-0315167-B1 Use of a synthetic resin compatibilizer NIPPON OILS & FATS CO LTD (JP) 1994-08-31 EP claimed
EP-0361203-B1 Synthetic resin compositions NIPPON OILS & FATS CO LTD (JP) 1994-04-27 EP claimed
EP-0289860-B1 ASSEMBLY OF SEVERAL LAYERS COMPRISING ONE OR MORE REINFORCING LAYERS AND PROCESS FOR PRODUCING A FIBER REINFORCED MATERIAL THE DOW CHEMICAL COMPANY (US) 1991-08-07 EP claimed
EP-0289860-A1 Assembly of several layers comprising one or more reinforcing layers and process for producing a fiber reinforced material THE DOW CHEMICAL COMPANY (US) 1988-11-09 EP claimed
EP-0138011-B1 POLY(P-PHENYLENETEREPHTHALAMIDE) FIBERS Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1987-11-04 EP claimed
EP-0222394-A2 Ultrasonic motor MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1987-05-20 EP claimed