Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | JAK2 | O60674 | 4/20 | 0.34 |
| ▸ | JAK1 | P23458 | 4/20 | 0.34 |
| ▸ | TYK2 | P29597 | 4/20 | 0.34 |
| ▸ | JAK3 | P52333 | 4/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28647956 | 0.96 | USP2 (0.35) | ALOX15JAK2JAK1TYK2JAK3 | |
| SCHEMBL28625576 | 0.91 | ALOX15 (0.37) | ALOX15JAK2JAK1TYK2JAK3 | |
| SCHEMBL29010336 | 0.82 | TSHR (0.34) | ALOX15CTNNB1LMNATSHRSMN1; SMN2 | |
| SCHEMBL31196271 | 0.79 | ALDH1A1 (0.36) | ALDH1A1LMNA | |
| SCHEMBL28602137 | 0.78 | ALOX15 (0.33) | ALOX15CTNNB1 | |
| SCHEMBL12705085 | 0.78 | PRKCA (0.31) | — | |
| SCHEMBL29007925 | 0.77 | ALOX15 (0.30) | ALOX15CTNNB1 | |
| Hydrochloric Acid SCHEMBL28602134 | 0.76 | ALOX15 (0.32) | ALOX15CTNNB1 | |
| SCHEMBL28882517 | 0.76 | USP2 (0.37) | ALOX15CTNNB1USP2ALDH1A1LMNA | |
| SCHEMBL15847736 | 0.75 | USP2 (0.39) | JAK2JAK1TYK2JAK3USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117229295-A | Nitrogen-containing macrocyclic compound, and preparation method and medical application thereof | 中国医药研究开发中心有限公司 | 2023-12-15 | — | — | CN | disclosed |