Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PRKCA | P17252 | 12/20 | 0.33 |
| ▸ | GALR3 | O60755 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7186589 | 0.94 | LMNA (0.34) | ALDH1A1LMNAHSD17B10PRKCA | |
| SCHEMBL30683844 | 0.85 | ALDH1A1 (0.40) | ALDH1A1LMNAHSD17B10GALR3 | |
| SCHEMBL7195368 | 0.83 | LMNA (0.39) | ALDH1A1LMNAHSD17B10GALR3 | |
| SCHEMBL16388604 | 0.82 | OPRM1 (0.33) | ALDH1A1LMNAHSD17B10PRKCA | |
| SCHEMBL13034076 | 0.80 | ALDH1A1 (0.38) | ALDH1A1LMNAHSD17B10PRKCA | |
| SCHEMBL8448704 | 0.80 | ALDH1A1 (0.43) | ALDH1A1LMNAHSD17B10PRKCAGALR3 | |
| SCHEMBL18134200 | 0.80 | ALDH1A1 (0.43) | ALDH1A1LMNAHSD17B10PRKCAGALR3 | |
| SCHEMBL29135764 | 0.79 | ALOX15 (0.34) | ALDH1A1LMNA | |
| SCHEMBL24920447 | 0.79 | ALDH1A1 (0.32) | ALDH1A1LMNAHSD17B10GALR3 | |
| SCHEMBL12705085 | 0.78 | PRKCA (0.31) | PRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709371-A1 | SMALL MOLECULE INHIBITORS OF KRAS G12D MUTANT | Merck Sharp & Dohme LLC (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233776-A1 | SMALL MOLECULE INHIBITORS OF KRAS G12D MUTANT | MERCK SHARP & DOHME LLC (US) | 2024-11-14 | — | — | WO | disclosed |