SCHEMBL2913591

SCHEMBL2913591

CCCOc1cc(NC(=O)CC(C)=O)ccc1NC(=O)CC(C)=O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.55
HSD17B10 Q99714 1/20 0.55
ALDH1A1 P00352 6/20 0.48
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
KDM4E B2RXH2 2/20 0.48
CYP1A2 P05177 1/20 0.48
CYP2C19 P33261 1/20 0.48
HIF1A Q16665 1/20 0.48
POLB P06746 1/20 0.47
GAA P10253 1/20 0.44
MAPK1 P28482 1/20 0.44
HPGD P15428 1/20 0.44
TSHR P16473 1/20 0.43
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
FAAH O00519 1/20 0.42
HDAC1 Q13547 1/20 0.41
HDAC8 Q9BY41 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2912941 0.93 POLB (0.52) MAPTHSD17B10ALDH1A1MEN1KMT2A
SCHEMBL2908421 0.89 KDM4E (0.51) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL2914555 0.82 MEN1 (0.66) MAPTHSD17B10ALDH1A1MEN1KMT2A
SCHEMBL2909815 0.79 MAPK1 (0.47) MAPTHSD17B10ALDH1A1MEN1KMT2A
SCHEMBL2906339 0.79 RORC (0.49) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL4544094 0.78 POLB (0.63) MAPTHSD17B10ALDH1A1MEN1KMT2A
SCHEMBL2914543 0.77 KMT2A (0.57) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL2907649 0.76 MEN1 (0.55) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL2913783 0.74 POLB (0.61) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL2904641 0.73 KMT2A (0.55) MAPTALDH1A1MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6756486-B1 LAKED DISAZO YELLOW PIGMENTS HAVING DESIRABLE GREEN SHADE, HEAT STABILITY, GOOD STRENGTH, BLEED RESISTANCE, MIGRATION RESISTANCE, AND LOW OR NO TOXICITY ENGELHARD CORPORATION 2004-06-29 US claimed
EP-1668080-B1 NON-MIGRATING MEALLIZED DISAZO GREEN SHADE YELLOW PIGMENT ENGELHARD CORP (US) 2010-08-11 EP disclosed
EP-1668080-A1 NON-MIGRATING MEALLIZED DISAZO GREEN SHADE YELLOW PIGMENT Engelhard Corporation (US) 2006-06-14 EP disclosed
WO-2005033212-A1 NON-MIGRATING MEALLIZED DISAZO GREEN SHADE YELLOW PIGMENT ENGELHARD CORPORATION (US) 2005-04-14 WO disclosed
US-6756486-B1 LAKED DISAZO YELLOW PIGMENTS HAVING DESIRABLE GREEN SHADE, HEAT STABILITY, GOOD STRENGTH, BLEED RESISTANCE, MIGRATION RESISTANCE, AND LOW OR NO TOXICITY ENGELHARD CORPORATION 2004-06-29 US disclosed
EP-1104444-B1 STRONG GREEN-SHADE YELLOW DISAZO PIGMENT ENGELHARD CORP (US) 2002-12-18 EP disclosed
US-6254671-B1 Very green-shade yellow metallized disazo pigment ENGELHARD CORPORATION 2001-07-03 US disclosed
EP-1104444-A1 STRONG GREEN-SHADE YELLOW DISAZO PIGMENT Engelhard Corporation (US) 2001-06-06 EP disclosed
WO-2001036540-A1 VERY GREEN-SHADE YELLOW METALLIZED DISAZO PIGMENT ENGELHARD CORPORATION (US) 2001-05-25 WO disclosed
WO-2000009614-A1 STRONG GREEN-SHADE YELLOW DISAZO PIGMENT ENGELHARD CORPORATION (US) 2000-02-24 WO disclosed
US-5889162-A COUPLING A DIAZONIUM COMPONENT MADE FROM ONE OR MORE AROMATIC AMINES SUCH AS 2-ETHOXYANILINE WITH AT LEAST ONE COUPLING AGENT; SUITABLE FOR USE IN PLASTICS, PAINTS AND INKS ENGELHARD CORPORATION (US) 1999-03-30 US disclosed
EP-0581245-B1 Water-insoluble azo colouring agents CLARIANT GMBH (DE) 1998-12-23 EP disclosed
EP-0585873-B1 Method of preparing disazo pigments CLARIANT GMBH (DE) 1997-12-29 EP disclosed
US-5559216-A AZO COUPLING HOECHST AG (DE) 1996-09-24 US disclosed
US-5428136-A Water-insoluble azo colorants having two azo groups and a 1,4-bis (acetoacetylamino) benzene coupling component HOECHST AG (DE) 1995-06-27 US disclosed
EP-0585873-A1 Method of preparing disazo pigments HOECHST AKTIENGESELLSCHAFT (DE) 1994-03-09 EP disclosed
EP-0581245-A1 Water-insoluble azo colouring agents HOECHST AKTIENGESELLSCHAFT (DE) 1994-02-02 EP disclosed