SCHEMBL2904641

SCHEMBL2904641

CC(=O)CC(=O)Nc1ccc(NC(=O)CC(C)=O)c(Br)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.55
ALDH1A1 P00352 4/20 0.55
MEN1 O00255 3/20 0.55
KDM4E B2RXH2 2/20 0.55
CYP1A2 P05177 1/20 0.55
CYP2C19 P33261 1/20 0.55
HIF1A Q16665 1/20 0.55
CA1 P00915 3/20 0.51
CA2 P00918 3/20 0.51
CA4 P22748 1/20 0.51
CA7 P43166 1/20 0.51
MAPT P10636 3/20 0.50
POLB P06746 2/20 0.46
TSHR P16473 1/20 0.46
HPGD P15428 3/20 0.46
GAA P10253 1/20 0.46
PKM P14618 1/20 0.46
LMNA P02545 1/20 0.44
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17509872 0.83 POLB (0.59) KMT2AALDH1A1MEN1KDM4ECYP1A2
SCHEMBL2908175 0.82 MAPT (0.47) KMT2AALDH1A1MEN1KDM4ECYP1A2
SCHEMBL1116483 0.82 ALDH1A1 (0.52) KMT2AALDH1A1MEN1KDM4ECA1
SCHEMBL16189542 0.82 KMT2A (0.54) KMT2AALDH1A1MEN1KDM4ECYP1A2
SCHEMBL2913783 0.81 POLB (0.61) KMT2AALDH1A1MEN1KDM4ECYP1A2
SCHEMBL2907649 0.80 MEN1 (0.55) KMT2AALDH1A1MEN1KDM4ECYP1A2
SCHEMBL2913865 0.80 MEN1 (0.61) KMT2AALDH1A1MEN1KDM4ECYP1A2
SCHEMBL5368510 0.80 KMT2A (0.55) KMT2AALDH1A1MEN1KDM4ECYP1A2
SCHEMBL19448886 0.80 PKM (0.68) KMT2AALDH1A1MEN1KDM4ECYP1A2
SCHEMBL11638580 0.79 CA1 (0.60) KMT2AALDH1A1MEN1KDM4ECYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6756486-B1 LAKED DISAZO YELLOW PIGMENTS HAVING DESIRABLE GREEN SHADE, HEAT STABILITY, GOOD STRENGTH, BLEED RESISTANCE, MIGRATION RESISTANCE, AND LOW OR NO TOXICITY ENGELHARD CORPORATION 2004-06-29 US claimed
EP-1668080-B1 NON-MIGRATING MEALLIZED DISAZO GREEN SHADE YELLOW PIGMENT ENGELHARD CORP (US) 2010-08-11 EP disclosed
US-7262284-B2 Method for producing disazo pigments CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) 2007-08-28 US disclosed
US-20060167236-A1 Method for producing disazo pigments CLARIANT GMBH (DE) 2006-07-27 US disclosed
EP-1668080-A1 NON-MIGRATING MEALLIZED DISAZO GREEN SHADE YELLOW PIGMENT Engelhard Corporation (US) 2006-06-14 EP disclosed
WO-2005033212-A1 NON-MIGRATING MEALLIZED DISAZO GREEN SHADE YELLOW PIGMENT ENGELHARD CORPORATION (US) 2005-04-14 WO disclosed
EP-1517962-A1 METHOD FOR PRODUCING DISAZO PIGMENTS Clariant GmbH (DE) 2005-03-30 EP disclosed
US-6756486-B1 LAKED DISAZO YELLOW PIGMENTS HAVING DESIRABLE GREEN SHADE, HEAT STABILITY, GOOD STRENGTH, BLEED RESISTANCE, MIGRATION RESISTANCE, AND LOW OR NO TOXICITY ENGELHARD CORPORATION 2004-06-29 US disclosed
WO-2004000947-A1 METHOD FOR PRODUCING DISAZO PIGMENTS CLARIANT GMBH (DE) 2003-12-31 WO disclosed
EP-1104444-B1 STRONG GREEN-SHADE YELLOW DISAZO PIGMENT ENGELHARD CORP (US) 2002-12-18 EP disclosed
EP-1104444-A1 STRONG GREEN-SHADE YELLOW DISAZO PIGMENT Engelhard Corporation (US) 2001-06-06 EP disclosed
WO-2001036540-A1 VERY GREEN-SHADE YELLOW METALLIZED DISAZO PIGMENT ENGELHARD CORPORATION (US) 2001-05-25 WO disclosed
WO-2000009614-A1 STRONG GREEN-SHADE YELLOW DISAZO PIGMENT ENGELHARD CORPORATION (US) 2000-02-24 WO disclosed
US-5889162-A COUPLING A DIAZONIUM COMPONENT MADE FROM ONE OR MORE AROMATIC AMINES SUCH AS 2-ETHOXYANILINE WITH AT LEAST ONE COUPLING AGENT; SUITABLE FOR USE IN PLASTICS, PAINTS AND INKS ENGELHARD CORPORATION (US) 1999-03-30 US disclosed
EP-0585873-B1 Method of preparing disazo pigments CLARIANT GMBH (DE) 1997-12-29 EP disclosed
US-5559216-A AZO COUPLING HOECHST AG (DE) 1996-09-24 US disclosed
US-5428136-A Water-insoluble azo colorants having two azo groups and a 1,4-bis (acetoacetylamino) benzene coupling component HOECHST AG (DE) 1995-06-27 US disclosed
EP-0585873-A1 Method of preparing disazo pigments HOECHST AKTIENGESELLSCHAFT (DE) 1994-03-09 EP disclosed
EP-0581245-A1 Water-insoluble azo colouring agents HOECHST AKTIENGESELLSCHAFT (DE) 1994-02-02 EP disclosed
EP-0025164-A1 Disazo compounds, process for their preparation and use HOECHST AKTIENGESELLSCHAFT (DE) 1981-03-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060167236-A1 Method for producing disazo pigments TYR, IPO4, CBR3 KMT2A 2138/4885ALDH1A1 560/4885MEN1 2054/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.