Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 7/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.33 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.33 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.33 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.33 |
| ▸ | GALR3 | O60755 | 1/20 | 0.33 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29136191 | 0.91 | MAPT (0.40) | CCR2PTGS2IDO1ALDH1A1MAPT | |
| SCHEMBL29136187 | 0.87 | P2RX3 (0.39) | CCR2KDM4EALDH1A1SOS1 | |
| SCHEMBL29136185 | 0.87 | CCR2 (0.52) | CCR2PTGS2KDM4EALDH1A1TP53 | |
| SCHEMBL29136176 | 0.84 | IDO1 (0.47) | CCR2IDO1KDM4EALDH1A1RAB9A | |
| SCHEMBL29136212 | 0.82 | DBH (0.42) | CCR2IDO1KDM4EALDH1A1RAB9A | |
| SCHEMBL17187081 | 0.81 | HTR2A (0.37) | CCR2KDM4EALDH1A1TP53MAPT | |
| SCHEMBL29136199 | 0.80 | CCR2 (0.55) | CCR2KDM4EALDH1A1TP53MAPT | |
| SCHEMBL16236116 | 0.78 | HTR2A (0.36) | ALDH1A1HTR2AHTR2C | |
| SCHEMBL29136200 | 0.77 | MAPT (0.46) | CCR2KDM4EALDH1A1TP53MAPT | |
| SCHEMBL29136196 | 0.74 | MAPT (0.43) | CCR2PTGS2KDM4EALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117003739-A | Nitrogen-containing heterocyclic compound, preparation method and application thereof | 安徽中医药大学 | 2023-11-07 | — | — | CN | disclosed |