Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29136191 | 0.87 | MAPT (0.40) | IDO1THRBALDH1A1SMN1; SMN2GAA | |
| SCHEMBL29136204 | 0.84 | HTT (0.45) | IDO1POLBALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL29136172 | 0.84 | CCR2 (0.38) | IDO1ALDH1A1RAB9AKDM4ECCR2 | |
| SCHEMBL29136199 | 0.80 | CCR2 (0.55) | ALDH1A1SMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL29136187 | 0.78 | P2RX3 (0.39) | ALDH1A1PPARGPPARAKDM4ECHRM5 | |
| SCHEMBL29136200 | 0.78 | MAPT (0.46) | ALDH1A1MGAMGAASIMGAM2 | |
| SCHEMBL29136185 | 0.75 | CCR2 (0.52) | POLBALDH1A1KMT2AKDM4ECCR2 | |
| SCHEMBL29136212 | 0.74 | DBH (0.42) | IDO1POLBALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL29136224 | 0.71 | IDO1 (0.46) | IDO1POLBTHRBALDH1A1SMN1; SMN2 | |
| SCHEMBL29136188 | 0.70 | RAB9A (0.42) | POLBALDH1A1SMN1; SMN2RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117003739-A | Nitrogen-containing heterocyclic compound, preparation method and application thereof | 安徽中医药大学 | 2023-11-07 | — | — | CN | disclosed |