Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29136194 | 0.80 | SLC6A2 (0.42) | MAPTKMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL29136212 | 0.80 | DBH (0.42) | ALDH1A1CYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL29136191 | 0.78 | MAPT (0.40) | MAPTKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL29136176 | 0.78 | IDO1 (0.47) | KMT2AMEN1HPGDALDH1A1L3MBTL1 | |
| SCHEMBL29136172 | 0.77 | CCR2 (0.38) | MAPTALDH1A1KDM4ECCR2TP53 | |
| SCHEMBL29136195 | 0.74 | SLC9A1 (0.48) | MAPTKMT2AMEN1ALDH1A1CYP1A2 | |
| SCHEMBL16236116 | 0.73 | HTR2A (0.36) | KMT2AALDH1A1HTR2AHTR6 | |
| SCHEMBL17187081 | 0.72 | HTR2A (0.37) | MAPTKMT2AHPGDALDH1A1L3MBTL1 | |
| SCHEMBL29136187 | 0.72 | P2RX3 (0.39) | ALDH1A1KDM4ECCR2 | |
| SCHEMBL29136185 | 0.69 | CCR2 (0.52) | MAPTKMT2AALDH1A1KDM4ECCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117003739-A | Nitrogen-containing heterocyclic compound, preparation method and application thereof | 安徽中医药大学 | 2023-11-07 | — | — | CN | disclosed |