Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | CCR2 | P41597 | 1/20 | 0.46 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CMA1 | P23946 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.39 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4384076 | 0.92 | KCNA3 (0.46) | MAPTTP53CCR2KCNA3HDAC11 | |
| SCHEMBL29136213 | 0.87 | CCR2 (0.51) | MAPTTP53CCR2LMNACMA1 | |
| SCHEMBL2117424 | 0.82 | HTR6 (0.48) | MAPTTP53KCNA3LMNAALDH1A1 | |
| SCHEMBL15062690 | 0.82 | IDO1 (0.39) | MAPTLMNAKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL29136198 | 0.81 | MAPT (0.46) | MAPTTP53LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL3091133 | 0.81 | P2RX4 (0.48) | MAPTTP53LMNAKDM4EALDH1A1 | |
| SCHEMBL4377626 | 0.78 | CACNB4 (0.45) | MAPTTP53KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL27789954 | 0.75 | CCR2 (0.52) | MAPTTP53CCR2LMNAKDM4E | |
| SCHEMBL29136224 | 0.74 | IDO1 (0.46) | LMNAKDM4EALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL29136178 | 0.74 | DBH (0.46) | KCNA3LMNAKDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117003739-A | Nitrogen-containing heterocyclic compound, preparation method and application thereof | 安徽中医药大学 | 2023-11-07 | — | — | CN | disclosed |