Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29136262 | 0.73 | GRM2 (0.50) | GRM2MMP1MMP13ALDH1A1SMN1; SMN2 | |
| SCHEMBL26114640 | 0.71 | GAA (0.46) | GRM2MMP1MMP13ALDH1A1LMNA | |
| SCHEMBL15757876 | 0.69 | GRM2 (0.53) | GRM2ALDH1A1LMNASMN1; SMN2MAPK1 | |
| SCHEMBL26116306 | 0.68 | GAA (0.51) | GRM2MMP1MMP13ALDH1A1LMNA | |
| SCHEMBL26103002 | 0.68 | GRM2 (0.51) | GRM2MMP1MMP9MMP13ADAM17 | |
| SCHEMBL31726969 | 0.68 | LMNA (0.52) | MMP1MMP9MMP13ADAM17ALDH1A1 | |
| SCHEMBL3988359 | 0.66 | LMNA (0.43) | MMP1MMP9MMP13ADAM17ALDH1A1 | |
| SCHEMBL13792676 | 0.66 | LMNA (0.43) | MMP1MMP9MMP13ADAM17ALDH1A1 | |
| SCHEMBL14686990 | 0.63 | MMP1 (0.62) | GRM2MMP1MMP9MMP13ALDH1A1 | |
| SCHEMBL8348748 | 0.63 | GRM2 (0.56) | GRM2MMP1MMP13ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114805168-B | Pyrrolinones and synthesis method thereof | 百顺药业有限公司 | 2024-01-09 | — | — | CN | disclosed |