Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | CMA1 | P23946 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29136230 | 0.83 | HPGD (0.42) | GRM2MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL18354002 | 0.78 | SIGMAR1 (0.44) | GRM2SIGMAR1GAAMMP1MMP13 | |
| SCHEMBL16927026 | 0.78 | SIGMAR1 (0.44) | GRM2SIGMAR1GAAMMP1MMP13 | |
| SCHEMBL7280963 | 0.74 | PKM (0.46) | GRM2SIGMAR1MEN1KMT2AGAA | |
| SCHEMBL7283527 | 0.74 | PKM (0.48) | GRM2SIGMAR1MEN1KMT2AGAA | |
| SCHEMBL20875902 | 0.73 | MEN1 (0.52) | GRM2SIGMAR1MEN1KMT2AGAA | |
| SCHEMBL20875900 | 0.73 | MEN1 (0.52) | GRM2SIGMAR1MEN1KMT2AGAA | |
| SCHEMBL29136236 | 0.73 | GRM2 (0.44) | GRM2MMP1MMP13ALDH1A1SMN1; SMN2 | |
| SCHEMBL14686990 | 0.71 | MMP1 (0.62) | GRM2MEN1KMT2AGAAMMP1 | |
| SCHEMBL8348748 | 0.71 | GRM2 (0.56) | GRM2MEN1KMT2AGAAMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114805168-B | Pyrrolinones and synthesis method thereof | 百顺药业有限公司 | 2024-01-09 | — | — | CN | disclosed |