SCHEMBL29136256

SCHEMBL29136256

C[SH2]c1ccc(C(=O)C(C)N2CCOCC2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 1/20 0.47
ALDH1A1 P00352 6/20 0.47
TSHR P16473 4/20 0.47
CYP3A4 P08684 1/20 0.47
CYP2C19 P33261 1/20 0.47
LMNA P02545 3/20 0.45
L3MBTL1 Q9Y468 2/20 0.42
MAPT P10636 3/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
KDM4E B2RXH2 1/20 0.42
GAA P10253 1/20 0.42
POLB P06746 1/20 0.42
KMT2A Q03164 1/20 0.42
CHRNB2 P17787 4/20 0.40
SLC6A2 P23975 4/20 0.40
CHRNB4 P30926 4/20 0.40
CHRNA3 P32297 4/20 0.40
CHRNA4 P43681 4/20 0.40
SLC6A3 Q01959 4/20 0.40
CHRNA1 P02708 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5813245 0.83 RAB9A (0.53) HRH3ALDH1A1TSHRCYP3A4CYP2C19
SCHEMBL3424629 0.82 ALDH1A1 (0.51) HRH3ALDH1A1TSHRCYP3A4CYP2C19
SCHEMBL10469275 0.82 HRH3 (0.49) HRH3ALDH1A1TSHRCYP3A4CYP2C19
SCHEMBL5954184 0.82 PHGDH (0.55) HRH3ALDH1A1TSHRCYP3A4CYP2C19
SCHEMBL321368 0.81 ALDH1A1 (0.67) ALDH1A1TSHRCYP3A4CYP2C19LMNA
Hydrochloric Acid SCHEMBL9596868 0.81 HRH3 (0.48) HRH3ALDH1A1TSHRCYP3A4CYP2C19
Hydrochloric Acid SCHEMBL10943241 0.80 ALDH1A1 (0.65) ALDH1A1TSHRCYP3A4CYP2C19LMNA
SCHEMBL1696905 0.79 ALDH1A1 (0.56) HRH3ALDH1A1TSHRCYP3A4CYP2C19
SCHEMBL10409601 0.78 L3MBTL1 (0.53) HRH3ALDH1A1TSHRLMNAL3MBTL1
Hydrochloric Acid SCHEMBL9596287 0.77 L3MBTL1 (0.52) ALDH1A1TSHRLMNAL3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114835868-B Preparation method of self-repairable and recyclable polymer nano composite film 合肥工业大学 2024-01-09 CN claimed