Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR5A | P47898 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30663578 | 1.00 | HTR5A (0.35) | HTR5APTPN11TGFBR1ALOX5APFEN1 | |
| SCHEMBL29866652 | 0.87 | HTR5A (0.32) | HTR5APTPN11TGFBR1 | |
| SCHEMBL27107027 | 0.82 | KDM4E (0.36) | HTR5AALOX5APFEN1 | |
| SCHEMBL30663590 | 0.78 | GABRG2 (0.41) | PTPN11GABRG2GABRB3GABRA5 | |
| SCHEMBL29136423 | 0.78 | CHRM2 (0.39) | — | |
| SCHEMBL29865942 | 0.78 | CHRM2 (0.39) | — | |
| SCHEMBL30703395 | 0.72 | DRD4 (0.47) | — | |
| SCHEMBL25897379 | 0.72 | DRD4 (0.47) | — | |
| SCHEMBL29865894 | 0.71 | PDE10A (0.32) | — | |
| SCHEMBL26677538 | 0.71 | PARP1 (0.39) | HRH4NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117120440-A | TYK2 inhibitor and application thereof | 苏多生物科学有限公司 | 2023-11-24 | — | — | CN | disclosed |