SCHEMBL29136474

SCHEMBL29136474

COC1(Cl)C=CC(/C=C\c2ccccc2)=CC1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.38
NFE2L2 Q16236 2/20 0.35
TUBB1 Q9H4B7 2/20 0.34
RELA Q04206 2/20 0.34
CHAT P28329 2/20 0.34
CYP1A1 P04798 2/20 0.34
CYP1A2 P05177 2/20 0.34
CYP1B1 Q16678 2/20 0.34
TUBB4A P04350 1/20 0.34
TUBB P07437 1/20 0.34
TUBA3C P0DPH7 1/20 0.34
TUBA1B P68363 1/20 0.34
TUBA4A P68366 1/20 0.34
TUBB4B P68371 1/20 0.34
TUBB3 Q13509 1/20 0.34
TUBB2A Q13885 1/20 0.34
TUBB8 Q3ZCM7 1/20 0.34
TUBA3E Q6PEY2 1/20 0.34
TUBA1A Q71U36 1/20 0.34
TUBA1C Q9BQE3 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11775251 0.82 TRPA1 (0.40) TRPA1NFE2L2TUBB1RELACHAT
SCHEMBL7006726 0.81 TRPA1 (0.39) TRPA1NFE2L2TUBB1RELACHAT
SCHEMBL28697334 0.80 CHAT (0.35) TRPA1NFE2L2RELACHATMEN1
SCHEMBL9040011 0.79 MAPT (0.43) RELACYP1A2CYP1B1MEN1ALDH1A1
SCHEMBL9344854 0.78 MAOB (0.37) TRPA1NFE2L2TUBB1RELACHAT
SCHEMBL7324466 0.77 TRPA1 (0.37) TRPA1NFE2L2CHATCYP1A2CMA1
SCHEMBL30781477 0.76 CHAT (0.39) TRPA1NFE2L2RELACHATCHRNB4
SCHEMBL4595773 0.76 CHAT (0.39) TRPA1NFE2L2RELACHATCHRNB4
SCHEMBL8323405 0.76 TRPA1 (0.38) TRPA1RELACYP1A2CYP1B1CMA1
SCHEMBL5741419 0.76 TRPA1 (0.35) TRPA1NFE2L2TUBB1RELACHAT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117362160-A Synthesis method of stilbene derivative Z-configuration isomer 广东克冠达医药科技有限公司 2024-01-09 CN disclosed