SCHEMBL8323405

SCHEMBL8323405

COC1(C(=O)O)C=CC(C=Cc2ccccc2)=CC1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.38
MMP1 P03956 3/20 0.38
MMP2 P08253 3/20 0.38
MMP9 P14780 3/20 0.38
EGFR P00533 2/20 0.37
ALDH1A1 P00352 3/20 0.37
MAPT P10636 3/20 0.37
MAOB P27338 3/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
HSPD1 P10809 1/20 0.37
TNFRSF1A P19438 1/20 0.37
HSPE1 P61604 1/20 0.37
CYP1B1 Q16678 1/20 0.37
CMA1 P23946 1/20 0.37
KDM4E B2RXH2 2/20 0.36
CYP3A4 P08684 2/20 0.36
HSD17B10 Q99714 2/20 0.36
USP2 O75604 1/20 0.36
TP53 P04637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8321851 0.88 FOS (0.46) MMP1MMP2MMP9ALDH1A1MAPT
SCHEMBL10802181 0.87 GLA (0.36) MMP1MMP2MMP9EGFRALDH1A1
Anethole SCHEMBL31387088 0.81 CYP3A4 (0.48) TRPA1MMP1MMP2MMP9EGFR
SCHEMBL5082374 0.79 HDAC1 (0.38) MMP1MMP2MMP9EGFRALDH1A1
SCHEMBL809497 0.79 HDAC1 (0.38) MMP1MMP2MMP9EGFRALDH1A1
SCHEMBL11775251 0.79 TRPA1 (0.40) TRPA1ALDH1A1MAPTMEN1KMT2A
SCHEMBL27447417 0.79 HDAC1 (0.38) MMP1MMP2MMP9EGFRALDH1A1
SCHEMBL9639696 0.78 ALDH1A1 (0.38) TRPA1MMP1MMP2MMP9EGFR
SCHEMBL7006726 0.77 TRPA1 (0.39) TRPA1ALDH1A1MAPTMAOBMEN1
Hydrochloric Acid SCHEMBL9546945 0.77 HDAC1 (0.37) MMP1MMP2MMP9EGFRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5989758-A EXHIBIT A LIQUID CRYSTALLINE PHASE AT TIME OF FUSION, WHICH CAN BE FIXED UPON COOLING BELOW THE LIQUID CRYSTALLINE TRANSITION TEMPERATURE; SPECIFIC MONOMERS 4,4'-STILBENEDIOLS, CATECHOLS, AND 4'-HYDROXY-4-STILBENECARBOXYLIC ACIDS NIPPON OIL COMPANY, LIMITED (JP) 1999-11-23 US disclosed