Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.31 |
| ▸ | TUBB | P07437 | 3/20 | 0.31 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.31 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.31 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.31 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.31 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.31 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29137339 | 0.89 | ALDH1A1 (0.33) | ALDH1A1KDM4EGAASMN1; SMN2L3MBTL1 | |
| SCHEMBL29137320 | 0.84 | TSHR (0.40) | KDM4EGAASMN1; SMN2ATMTUBB4A | |
| SCHEMBL29137252 | 0.82 | TDP2 (0.37) | ALDH1A1MAPK1TUBB4ATUBBTUBA3C | |
| SCHEMBL29137345 | 0.82 | TUBB4A (0.32) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL29137223 | 0.82 | SMN1; SMN2 (0.34) | SMN1; SMN2ATMTUBB4ATUBBTUBA3C | |
| SCHEMBL29137286 | 0.81 | CYP1A1 (0.41) | ALDH1A1KDM4EGAASMN1; SMN2MAPT | |
| SCHEMBL29137336 | 0.81 | KDM4E (0.36) | ALDH1A1KDM4EPARP1 | |
| SCHEMBL29137325 | 0.80 | MEN1 (0.35) | ALDH1A1SMN1; SMN2MAPTHTR7MEN1 | |
| SCHEMBL29137242 | 0.79 | POLB (0.47) | ALDH1A1KDM4EGAASMN1; SMN2L3MBTL1 | |
| SCHEMBL29137298 | 0.78 | POLB (0.37) | ALDH1A1KDM4ESMN1; SMN2L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117326923-A | Fluorine-containing dihydronaphthalenone derivative and preparation method and application thereof | 上海应用技术大学 | 2024-01-02 | — | — | CN | disclosed |