Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29137719 | 0.89 | HDAC1 (0.39) | HDAC1HDAC6ALDH1A1HIF1AMAPT | |
| SCHEMBL30768173 | 0.89 | HDAC1 (0.39) | HDAC1HDAC6ALDH1A1HIF1AMAPT | |
| SCHEMBL29137734 | 0.88 | APP (0.41) | HDAC1HDAC6ALDH1A1HIF1AGAA | |
| SCHEMBL29137736 | 0.88 | APP (0.41) | HDAC1HDAC6ALDH1A1HIF1AGAA | |
| SCHEMBL8282320 | 0.79 | ALDH1A1 (0.43) | HDAC1HDAC6ALDH1A1HIF1AGAA | |
| SCHEMBL4826032 | 0.78 | ALDH1A1 (0.52) | HDAC1HDAC6ALDH1A1HIF1AGAA | |
| SCHEMBL112764 | 0.76 | AKR1C3 (0.59) | HIF1AMAPTPTGS2PTGS1CYP2C19 | |
| SCHEMBL13172090 | 0.76 | AKR1C3 (0.47) | HDAC1HDAC6HIF1AMAPTPTGS2 | |
| SCHEMBL24875457 | 0.75 | MT-CO2 (0.47) | HDAC1HDAC6HIF1AMAPTPTGS2 | |
| SCHEMBL8476208 | 0.75 | MT-CO2 (0.47) | HDAC1HDAC6HIF1AMAPTPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117384153-A | Methyltransferase inhibitors and uses thereof | 上海赛岚生物科技有限公司 | 2024-01-12 | — | — | CN | disclosed |