Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | SCN4A | P35499 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21138713 | 0.84 | ALDH1A1 (0.52) | ALDH1A1HTTGAAALOX12HIF1A | |
| SCHEMBL8282311 | 0.83 | ALDH1A1 (0.46) | ALDH1A1HTTGAAALOX12HIF1A | |
| Hydrochloric Acid SCHEMBL30283024 | 0.82 | ALDH1A1 (0.50) | ALDH1A1HTTGAAALOX12HIF1A | |
| SCHEMBL8214575 | 0.82 | ALDH1A1 (0.57) | ALDH1A1HTTGAAALOX12HIF1A | |
| SCHEMBL1597071 | 0.81 | ALDH1A1 (0.54) | ALDH1A1HTTGAAALOX12HIF1A | |
| SCHEMBL8282821 | 0.81 | ALDH1A1 (0.45) | ALDH1A1HTTGAAALOX12HIF1A | |
| SCHEMBL20226510 | 0.79 | ALDH1A1 (0.58) | ALDH1A1GAACA12CA1CA2 | |
| SCHEMBL5381547 | 0.79 | ALDH1A1 (0.43) | ALDH1A1HTTGAAALOX12HIF1A | |
| SCHEMBL25676390 | 0.79 | ALDH1A1 (0.58) | ALDH1A1GAACA12CA1CA2 | |
| SCHEMBL8282320 | 0.79 | ALDH1A1 (0.43) | ALDH1A1HTTGAAALOX12HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026102082-A1 | ALKYLPHENYL SUBSTITUTED COMPOUNDS, COMPOSITIONS AND METHODS OF USE | DEEP APPLE THERAPEUTICS, INC. (US) | 2026-05-15 | — | — | WO | disclosed |
| US-20260132119-A1 | Alkylphenyl Substituted Compounds, Compositions and Methods of Use | DEEP APPLE THERAPEUTICS, INC. (US) | 2026-05-14 | — | — | US | disclosed |
| EP-4313981-B1 | 3,4-DIHYDRO-2,7-NAPHTHYRIDINE-1,6(2H,7H)-DIONES AS MEK INHIBITORS | PFIZER (US) | 2026-02-25 | — | — | EP | disclosed |
| US-20250263411-A1 | 3,4-DIHYDRO-2,7-NAPHTHYRIDINE-1,6(2H,7H)-DIONES AS MEK INHIBITORS | PFIZER INC. (US) | 2025-08-21 | — | — | US | disclosed |
| CN-117561255-A | 3, 4-dihydro-2, 7-naphthyridine-1, 6 (2H, 7H) -dione compounds as MEK inhibitors | 辉瑞公司 | 2024-02-13 | — | — | CN | disclosed |
| EP-4313981-A1 | 3,4-DIHYDRO-2,7-NAPHTHYRIDINE-1,6(2H,7H)-DIONES AS MEK INHIBITORS | Pfizer Inc. (US) | 2024-02-07 | — | — | EP | disclosed |
| US-20240002384-A1 | 3,4-DIHYDRO-2,7-NAPHTHYRIDINE-1,6(2H,7H)-DIONES AS MEK INHIBITORS | PFIZER INC. (US) | 2024-01-04 | — | — | US | disclosed |
| US-11802127-B2 | 3,4-dihydro-2,7-naphthyridine-1,6(2H,7H)-diones as MEK inhibitors | PFIZER INC. (US) | 2023-10-31 | — | — | US | disclosed |
| US-11760775-B2 | Steroids and protein-conjugates thereof | REGENERON PHARMACEUTICALS, INC. | 2023-09-19 | — | — | US | disclosed |
| US-11760775-B2 | Steroids and protein-conjugates thereof | REGENERON PHARMACEUTICALS, INC. | 2023-09-19 | — | — | US | disclosed |
| US-7238692-B2 | Medical devices employing triazine compounds and compositions thereof | REDDY US THERAPEUTICS, INC. (US) | 2007-07-03 | — | — | US | disclosed |
| US-7169785-B2 | Methods and compositions of novel triazine compounds | REDDY US THERAPEUTICS, INC. (US) | 2007-01-30 | — | — | US | disclosed |
| US-7169785-B2 | Methods and compositions of novel triazine compounds | REDDY US THERAPEUTICS, INC. (US) | 2007-01-30 | — | — | US | disclosed |
| US-20050143454-A1 | 4-Alkyl-2-haloaniline derivative and process and process for producing the same | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2005-06-30 | — | — | US | disclosed |
| EP-1506954-A1 | 4-ALKYL-2-HALOANILINE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | MEIJI SEIKA KAISHA LTD. (JP) | 2005-02-16 | — | — | EP | disclosed |
| US-5068435-A | Alkylation of amines with alkenes in the presence of alumina catalyst | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1991-11-26 | — | — | US | disclosed |
| EP-0334332-A1 | Ortho-alkylated aromatic amines via gamma alumina catalyst | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1989-09-27 | — | — | EP | disclosed |
| EP-0079093-B1 | PROCESS FOR THE SELECTIVE ALKYLATION OF AN ANILINE | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1986-06-11 | — | — | EP | disclosed |
| US-4436937-A | ALUMINUM HALIDE CATALYST | SHELL OIL COMPANY (US) | 1984-03-13 | — | — | US | disclosed |
| EP-0079093-A1 | Process for the selective alkylation of an aniline | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1983-05-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143454-A1 | 4-Alkyl-2-haloaniline derivative and process and process for producing the same | NAT1, CYP4X1, HAX1 | ALDH1A1 441/4885HTT 230/4885GAA 2026/4885 |
| US-20240002384-A1 | 3,4-DIHYDRO-2,7-NAPHTHYRIDINE-1,6(2H,7H)-DIONES AS MEK INHIBITORS | NRAS, KRAS, BRAF | ALDH1A1 1249/4885HTT 3879/4885GAA 2349/4885 |
| US-20250263411-A1 | 3,4-DIHYDRO-2,7-NAPHTHYRIDINE-1,6(2H,7H)-DIONES AS MEK INHIBITORS | NRAS, KRAS, BRAF | ALDH1A1 1249/4885HTT 3879/4885GAA 2349/4885 |
| US-11802127-B2 | 3,4-dihydro-2,7-naphthyridine-1,6(2H,7H)-diones as MEK inhibitors | NRAS, KRAS, MAPK1 | ALDH1A1 701/4885HTT 3265/4885GAA 3638/4885 |
| US-20260132119-A1 | Alkylphenyl Substituted Compounds, Compositions and Methods of Use | GIPR, MC2R, GRPR | ALDH1A1 3360/4885HTT 1205/4885GAA 633/4885 |
| US-11760775-B2 | Steroids and protein-conjugates thereof | SERPINA6, NR3C1, NR3C2 | ALDH1A1 4113/4885HTT 3404/4885GAA 2422/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.