Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IFNAR1 | P17181 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5071846 | 0.93 | IFNAR1 (0.37) | IFNAR1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8038665 | 0.89 | IFNAR1 (0.41) | IFNAR1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL6293960 | 0.88 | IFNAR1 (0.43) | IFNAR1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL2607673 | 0.81 | TLR8 (0.50) | IFNAR1ALDH1A1LMNAMAPK1NPY1R | |
| SCHEMBL11552030 | 0.81 | HTR1B (0.47) | IFNAR1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL2607768 | 0.81 | ALDH1A1 (0.45) | IFNAR1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL1156874 | 0.80 | IFNAR1 (0.43) | IFNAR1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL18758015 | 0.80 | PTGS2 (0.49) | IFNAR1ALDH1A1LMNAMAPK1NPY1R | |
| SCHEMBL30417186 | 0.80 | PTGS2 (0.49) | IFNAR1ALDH1A1LMNAMAPK1NPY1R | |
| SCHEMBL5316461 | 0.79 | PTGS2 (0.50) | IFNAR1ALDH1A1LMNAMAPK1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000079312-A1 | HIGH REFRACTIVE INDEX COMPOSITIONS FOR OPHTHALMIC IMPLANTS | BAUSCH & LOMB SURGICAL, INC. (US) | 2000-12-28 | — | — | WO | disclosed |