SCHEMBL29137974

SCHEMBL29137974

NC(=O)Oc1cc2c(C=O)c(F)ccc2cn1

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 5/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29137983 0.76 MEN1 (0.37) ERN1
SCHEMBL29137925 0.72 MAPT (0.44)
SCHEMBL29137957 0.71 ERN1 (0.36) ERN1
SCHEMBL29137977 0.69 PARP1 (0.39)
SCHEMBL4073461 0.67 PLAU (0.46)
SCHEMBL30636265 0.67 PLAU (0.46)
SCHEMBL28602515 0.67 KIF11 (0.32) ERN1
Hydrochloric Acid SCHEMBL19182207 0.66 NNMT (0.33)
SCHEMBL28749667 0.66 NNMT (0.33)
SCHEMBL26933417 0.66 BACE1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117062804-A 1, 3-substituted cyclobutyl derivatives and their use 诺华股份有限公司 2023-11-14 CN disclosed