Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.33 |
| ▸ | STAMBP | O95630 | 1/20 | 0.33 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 6/20 | 0.32 |
| ▸ | PARP1 | P09874 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29137977 | 0.88 | PARP1 (0.39) | MEN1KMT2APSMD14STAMBPCOPS5 | |
| SCHEMBL29137974 | 0.76 | ERN1 (0.34) | ERN1 | |
| SCHEMBL4073461 | 0.76 | PLAU (0.46) | MEN1KMT2APSMD14STAMBPCOPS5 | |
| SCHEMBL30636265 | 0.76 | PLAU (0.46) | MEN1KMT2APSMD14STAMBPCOPS5 | |
| SCHEMBL29137957 | 0.73 | ERN1 (0.36) | ALDH1A1ERN1L3MBTL1 | |
| SCHEMBL23976011 | 0.71 | GABRP (0.37) | MEN1KMT2AALDH1A1HPGDHTT | |
| SCHEMBL29113189 | 0.69 | MAPT (0.38) | MEN1KMT2AERN1 | |
| SCHEMBL4020792 | 0.69 | LMNA (0.39) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL17477194 | 0.66 | ALDH1A1 (0.49) | KMT2APTGDR2ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL28475692 | 0.66 | MEN1 (0.41) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117062804-A | 1, 3-substituted cyclobutyl derivatives and their use | 诺华股份有限公司 | 2023-11-14 | — | — | CN | disclosed |