Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.39 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.33 |
| ▸ | STAMBP | O95630 | 1/20 | 0.33 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | PLK4 | O00444 | 1/20 | 0.30 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.30 |
| ▸ | AURKA | O14965 | 1/20 | 0.30 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.30 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.30 |
| ▸ | CSF1R | P07333 | 1/20 | 0.30 |
| ▸ | RET | P07949 | 1/20 | 0.30 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.30 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29137983 | 0.88 | MEN1 (0.37) | PARP1MEN1KMT2APIM1PSMD14 | |
| SCHEMBL4073461 | 0.75 | PLAU (0.46) | PARP1MEN1KMT2APSMD14STAMBP | |
| SCHEMBL30636265 | 0.75 | PLAU (0.46) | PARP1MEN1KMT2APSMD14STAMBP | |
| SCHEMBL29137986 | 0.74 | — | — | |
| SCHEMBL2145623 | 0.70 | CYP1A2 (0.48) | PARP1MEN1KMT2APSMD14COPS5 | |
| SCHEMBL26933015 | 0.70 | ALDH1A1 (0.38) | PARP1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL29890165 | 0.70 | ALDH1A1 (0.38) | PARP1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL29137974 | 0.69 | ERN1 (0.34) | — | |
| SCHEMBL4020792 | 0.68 | LMNA (0.39) | MEN1KMT2AKDM4EALDH1A1HSD17B10 | |
| SCHEMBL28849760 | 0.67 | PARP1 (0.40) | PARP1MEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117062804-A | 1, 3-substituted cyclobutyl derivatives and their use | 诺华股份有限公司 | 2023-11-14 | — | — | CN | disclosed |