SCHEMBL1906185

SCHEMBL1906185

CO[Si](OC)(c1cccc2c1Cc1ccccc1-2)c1cccc2c1Cc1ccccc1-2

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.45
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
HIF1A Q16665 3/20 0.39
KDR P35968 1/20 0.37
KDM4E B2RXH2 1/20 0.37
MEN1 O00255 1/20 0.37
ALDH1A1 P00352 1/20 0.37
MAPT P10636 1/20 0.37
KMT2A Q03164 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
HTR7 P34969 1/20 0.37
HTR2B P41595 1/20 0.37
DRD2 P14416 1/20 0.36
DRD4 P21917 1/20 0.36
DRD3 P35462 1/20 0.36
PGR P06401 1/20 0.35
PDGFRB P09619 1/20 0.35
CDK1 P06493 1/20 0.35
CDK2 P24941 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30689028 0.86 PNMT (0.45) PNMTNPC1RAB9AHIF1AKDR
SCHEMBL1985427 0.86 PNMT (0.45) PNMTNPC1RAB9AHIF1AKDR
SCHEMBL29138460 0.84 PNMT (0.36) PNMTNPC1RAB9AHIF1AKDR
SCHEMBL8971825 0.81 PNMT (0.46) PNMTNPC1RAB9AHIF1AKDR
SCHEMBL6671922 0.80 PNMT (0.49) PNMTNPC1RAB9AKDRKDM4E
SCHEMBL5981385 0.80 PNMT (0.49) PNMTNPC1RAB9AHIF1AKDR
SCHEMBL61027 0.80 PNMT (0.49) PNMTNPC1RAB9AKDRKDM4E
SCHEMBL29843943 0.80 PNMT (0.49) PNMTNPC1RAB9AKDRKDM4E
SCHEMBL30745574 0.80 PNMT (0.52) PNMTNPC1RAB9AKDRKDM4E
SCHEMBL30745575 0.80 PNMT (0.52) PNMTNPC1RAB9AKDRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 218 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107428716-B Catalyst system, olefin polymerization catalyst component comprising at least an internal electron donor compound, and methods of making and using the same 格雷斯公司 2021-05-11 CN claimed
CN-109134720-B External electron donors for olefin polymerization 印度石油有限公司 2021-03-05 CN claimed
US-10689465-B2 External donor for olefin polymerization INDIAN OIL CORPORATION LIMITED (IN) 2020-06-23 US claimed
EP-3653631-A1 PROCESSES FOR THE PREPARATION OF AN OLEFIN POLYMERIZATION CATALYST BASED ON TREATING SOLID ORGANOMAGNESIUM COMPOUNDS WITH TITANIUM MOIETIES INDIAN OIL CORPORATION Ltd. (IN) 2020-05-20 EP claimed
US-10611865-B2 Organometallic compound in solid form, process for preparing the same and use thereof INDIAN OIL CORPORATION LIMITED (IN) 2020-04-07 US claimed
US-20180362675-A1 EXTERNAL DONOR FOR OLEFIN POLYMERIZATION INDIAN OIL CORPORATION LIMITED (IN) 2018-12-20 US claimed
EP-3415541-A1 EXTERNAL DONOR FOR OLEFIN POLYMERIZATION INDIAN OIL CORPORATION Ltd. (IN) 2018-12-19 EP claimed
US-20180355082-A1 ORGANOMETALLIC COMPOUND IN SOLID FORM, PROCESS FOR PREPARING THE SAME AND USE THEREOF INDIAN OIL CORPORATION LIMITED (IN) 2018-12-13 US claimed
US-20170081440-A1 ORGANOMETALLIC COMPOUND IN SOLID FORM, PROCESS FOR PREPARING THE SAME AND USE THEREOF INDIAN OIL CORPORATION LIMITED (IN) 2017-03-23 US claimed
US-20150274857-A1 DISTANCE MEASURING METHOD AND DISTANCE MEASURING ELEMENT INDIAN OIL CORPORATION LIMITED (IN) 2015-10-01 US claimed
EP-2897965-A2 PRECURSOR FOR CATALYST, PROCESS FOR PREPARING THE SAME AND ITS USE THEREOF Indian Oil Corporation Ltd (IN) 2015-07-29 EP claimed
EP-2897966-A2 ORGANOMETALLIC COMPOUND IN SOLID FORM, PROCESS FOR PREPARING THE SAME AND USE THEREOF Indian Oil Corporation Ltd (IN) 2015-07-29 EP claimed
US-20150191553-A1 ORGANOMETALLIC COMPOUND IN SOLID FORM, PROCESS FOR PREPARING THE SAME AND USE THEREOF INDIAN OIL CORPORATION LIMITED (IN) 2015-07-09 US claimed
WO-2014045259-A2 PRECURSOR FOR CATALYST, PROCESS FOR PREPARING THE SAME AND ITS USE THEREOF INDIAN OIL CORPORATION LIMITED (IN) 2014-03-27 WO claimed
WO-2014045260-A2 ORGANOMETALLIC COMPOUND IN SOLID FORM, PROCESS FOR PREPARING THE SAME AND USE THEREOF INDIAN OIL CORPORATION LIMITED (IN) 2014-03-27 WO claimed
EP-3676300-B1 OLEFIN POLYMERIZATION CATALYST GRACE W R & CO (US) 2026-05-13 EP disclosed
EP-3592783-B1 ELECTRON DONORS FOR ZIEGLER-NATTA PRECATALYST PREPARATION AND CATALYST SYSTEM FOR OLEFIN POLYMERIZATION GRACE W R & CO (US) 2025-11-12 EP disclosed
EP-0350170-B1 Process for polymerising olefins and polymerisation catalyst therefor MITSUI PETROCHEMICAL IND (JP) 1994-03-02 EP disclosed
US-4990479-A Coordination catalysts MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-02-05 US disclosed
EP-0350170-A2 Process for polymerising olefins and polymerisation catalyst therefor MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1990-01-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180355082-A1 ORGANOMETALLIC COMPOUND IN SOLID FORM, PROCESS FOR PREPARING THE SAME AND USE THEREOF MLX, BRIX1, CYP4X1 PNMT 3587/4885NPC1 3292/4885RAB9A 2741/4885
US-10611865-B2 Organometallic compound in solid form, process for preparing the same and use thereof MLX, BRIX1, CYP4X1 PNMT 3587/4885NPC1 3292/4885RAB9A 2741/4885
US-20150274857-A1 DISTANCE MEASURING METHOD AND DISTANCE MEASURING ELEMENT MLX, PRDX2, NFXL1 PNMT 3058/4885NPC1 2682/4885RAB9A 2237/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.