Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.49 |
| ▸ | DRD3 | P35462 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.47 |
| ▸ | HTR3B | O95264 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | HTR3A | P46098 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.47 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29138525 | 0.86 | DRD2 (0.53) | DRD2DRD3HPGDALDH1A1MAPT | |
| SCHEMBL3436353 | 0.83 | ALDH1A1 (0.48) | HPGDALDH1A1MAPTAKR1C3ADRB1 | |
| SCHEMBL3435988 | 0.81 | MEN1 (0.45) | HPGDALDH1A1MAPT | |
| SCHEMBL4776267 | 0.81 | DRD2 (0.49) | DRD2DRD3HPGDALDH1A1MAPT | |
| SCHEMBL29138547 | 0.78 | DRD2 (0.56) | DRD2DRD3HPGDALDH1A1MAPT | |
| SCHEMBL9684198 | 0.77 | ALDH1A1 (0.50) | ALDH1A1MAPTADRB1LMNATSHR | |
| SCHEMBL25603132 | 0.77 | NOTUM (0.53) | HPGDALDH1A1MAPTCYP2C19HTT | |
| SCHEMBL3435051 | 0.77 | MAPT (0.54) | ALDH1A1MAPTLMNAHTTHTR1A | |
| SCHEMBL34462822 | 0.75 | DRD2 (0.56) | DRD2DRD3HPGDALDH1A1MAPT | |
| SCHEMBL18580808 | 0.75 | JAK2 (0.38) | DRD3ALDH1A1MAPTLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117069720-A | 5-HT 2A Receptor agonist, preparation method and application thereof | 上海翊石医药科技有限公司 | 2023-11-17 | — | — | CN | disclosed |