Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 6/20 | 0.49 |
| ▸ | TSHR | P16473 | 4/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3436353 | 0.88 | ALDH1A1 (0.48) | ALDH1A1KMT2AMAPTMEN1TSHR | |
| SCHEMBL18580808 | 0.85 | JAK2 (0.38) | ALDH1A1KMT2AMAPTMEN1TSHR | |
| SCHEMBL3435988 | 0.77 | MEN1 (0.45) | ALDH1A1KMT2AMAPTMEN1NPSR1 | |
| SCHEMBL29138516 | 0.77 | DRD2 (0.49) | ALDH1A1MAPTTSHRLMNAADRB1 | |
| SCHEMBL1500721 | 0.75 | ADRB1 (0.53) | ALDH1A1KMT2AMAPTMEN1TSHR | |
| SCHEMBL12728148 | 0.73 | AKR1C3 (0.42) | ALDH1A1KMT2AMAPTMEN1TSHR | |
| SCHEMBL25983414 | 0.73 | NOTUM (0.59) | ALDH1A1KMT2AMAPTMEN1ADRB1 | |
| SCHEMBL3435051 | 0.72 | MAPT (0.54) | ALDH1A1KMT2AMAPTMEN1NPSR1 | |
| SCHEMBL30755129 | 0.72 | PTGES (0.50) | KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL25603132 | 0.72 | NOTUM (0.53) | ALDH1A1KMT2AMAPTMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130309-A | Cardiovascular disorders | A. H. ROBINS COMPANY, INCORPORATED (US) | 1992-07-14 | — | — | US | disclosed |