SCHEMBL2913865

SCHEMBL2913865

CC(=O)CC(=O)Nc1ccc(NC(=O)CC(C)=O)c(Cl)c1

nearest known ligand 0.61

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.61
KMT2A Q03164 4/20 0.61
ALDH1A1 P00352 4/20 0.55
KDM4E B2RXH2 1/20 0.55
CYP1A2 P05177 1/20 0.55
CYP2C19 P33261 1/20 0.55
HIF1A Q16665 1/20 0.55
GAA P10253 1/20 0.55
NPSR1 Q6W5P4 1/20 0.55
CYP3A4 P08684 1/20 0.54
HPGD P15428 3/20 0.50
MAPT P10636 1/20 0.50
TSHR P16473 1/20 0.50
USP2 O75604 1/20 0.50
LMNA P02545 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9283532 0.93 MEN1 (0.55) MEN1KMT2AALDH1A1KDM4ECYP1A2
SCHEMBL9824009 0.86 CYP3A4 (0.72) MEN1KMT2AALDH1A1KDM4ECYP1A2
SCHEMBL11222525 0.85 MEN1 (0.51) MEN1KMT2AALDH1A1KDM4EGAA
SCHEMBL9180503 0.85 HPGD (0.68) MEN1KMT2AALDH1A1KDM4ECYP1A2
SCHEMBL31590796 0.85 HPGD (0.68) MEN1KMT2AALDH1A1KDM4ECYP1A2
SCHEMBL31570084 0.83 MEN1 (0.57) MEN1KMT2AALDH1A1KDM4EGAA
SCHEMBL12531500 0.83 HPGD (0.68) MEN1KMT2AALDH1A1KDM4ECYP1A2
SCHEMBL9292088 0.83 MEN1 (0.57) MEN1KMT2AALDH1A1KDM4EGAA
SCHEMBL2914539 0.82 ALDH1A1 (0.54) MEN1KMT2AALDH1A1KDM4ECYP1A2
SCHEMBL1116467 0.82 NPSR1 (0.61) MEN1KMT2AALDH1A1NPSR1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6756486-B1 LAKED DISAZO YELLOW PIGMENTS HAVING DESIRABLE GREEN SHADE, HEAT STABILITY, GOOD STRENGTH, BLEED RESISTANCE, MIGRATION RESISTANCE, AND LOW OR NO TOXICITY ENGELHARD CORPORATION 2004-06-29 US claimed
EP-0581245-B1 Water-insoluble azo colouring agents CLARIANT GMBH (DE) 1998-12-23 EP claimed
EP-0581245-A1 Water-insoluble azo colouring agents HOECHST AKTIENGESELLSCHAFT (DE) 1994-02-02 EP claimed
EP-1668080-B1 NON-MIGRATING MEALLIZED DISAZO GREEN SHADE YELLOW PIGMENT ENGELHARD CORP (US) 2010-08-11 EP disclosed
US-7262284-B2 Method for producing disazo pigments CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) 2007-08-28 US disclosed
US-20060167236-A1 Method for producing disazo pigments CLARIANT GMBH (DE) 2006-07-27 US disclosed
EP-1668080-A1 NON-MIGRATING MEALLIZED DISAZO GREEN SHADE YELLOW PIGMENT Engelhard Corporation (US) 2006-06-14 EP disclosed
WO-2005033212-A1 NON-MIGRATING MEALLIZED DISAZO GREEN SHADE YELLOW PIGMENT ENGELHARD CORPORATION (US) 2005-04-14 WO disclosed
EP-1517962-A1 METHOD FOR PRODUCING DISAZO PIGMENTS Clariant GmbH (DE) 2005-03-30 EP disclosed
US-6756486-B1 LAKED DISAZO YELLOW PIGMENTS HAVING DESIRABLE GREEN SHADE, HEAT STABILITY, GOOD STRENGTH, BLEED RESISTANCE, MIGRATION RESISTANCE, AND LOW OR NO TOXICITY ENGELHARD CORPORATION 2004-06-29 US disclosed
WO-2004000947-A1 METHOD FOR PRODUCING DISAZO PIGMENTS CLARIANT GMBH (DE) 2003-12-31 WO disclosed
US-5428136-A Water-insoluble azo colorants having two azo groups and a 1,4-bis (acetoacetylamino) benzene coupling component HOECHST AG (DE) 1995-06-27 US disclosed
EP-0585873-A1 Method of preparing disazo pigments HOECHST AKTIENGESELLSCHAFT (DE) 1994-03-09 EP disclosed
EP-0581245-A1 Water-insoluble azo colouring agents HOECHST AKTIENGESELLSCHAFT (DE) 1994-02-02 EP disclosed
EP-0053260-B1 PHOTOSENSIBLE MULTILAYER MATERIAL AND PROCESS FOR ITS PRODUCTION BASF Aktiengesellschaft (DE) 1984-02-01 EP disclosed
EP-0053260-A1 Photosensible multilayer material and process for its production BASF Aktiengesellschaft (DE) 1982-06-09 EP disclosed
EP-0025164-A1 Disazo compounds, process for their preparation and use HOECHST AKTIENGESELLSCHAFT (DE) 1981-03-18 EP disclosed
US-4221709-A Azo pigments DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) 1980-09-09 US disclosed
US-3988312-A TETRAKISAZO DYES CIBA-GEIGY CORPORATION (US) 1976-10-26 US disclosed
US-3978038-A POLYAMIDES, POLYESTERS, POLYURETHANES CIBA-GEIGY CORPORATION (US) 1976-08-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060167236-A1 Method for producing disazo pigments TYR, IPO4, CBR3 MEN1 2054/4885KMT2A 2138/4885ALDH1A1 560/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.