Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 7/20 | 0.66 |
| ▸ | ADORA2A | P29274 | 10/20 | 0.63 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.63 |
| ▸ | PI4KA | P42356 | 3/20 | 0.63 |
| ▸ | PI4K2B | Q8TCG2 | 3/20 | 0.63 |
| ▸ | PI4K2A | Q9BTU6 | 3/20 | 0.63 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.63 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7680204 | 0.83 | AHCY (0.66) | AHCYADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL11222112 | 0.80 | ADORA2A (0.80) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL28454215 | 0.80 | FDPS (0.51) | AHCYADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL12925855 | 0.79 | ADORA2A (0.71) | AHCYADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL28950118 | 0.78 | AHCY (0.48) | AHCYADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL1924594 | 0.77 | ADORA2A (1.00) | AHCYADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL22558037 | 0.77 | ADORA2A (0.69) | AHCYADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL2495370 | 0.77 | ADORA2A (0.69) | AHCYADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL1871838 | 0.77 | ADORA2A (0.75) | AHCYADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL3441186 | 0.76 | CDK1 (0.54) | ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106883217-B | Nucleoside base hydroxamic acid derivative compound and preparation method and application thereof | 清华大学深圳研究生院 | 2020-05-22 | — | — | CN | disclosed |
| US-10308638-B2 | Selective alpha-7 nicotinic receptor agonists and methods for making and using them | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-06-04 | — | — | US | disclosed |
| US-20180244653-A1 | SELECTIVE ALPHA-7 NICOTINIC RECEPTOR AGONISTS AND METHODS FOR MAKING AND USING THEM | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2018-08-30 | — | — | US | disclosed |
| US-9896461-B2 | Polysilylated organosilane compounds | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S) (FR) | 2018-02-20 | — | — | US | disclosed |
| US-9896461-B2 | Polysilylated organosilane compounds | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S) (FR) | 2018-02-20 | — | — | US | disclosed |
| WO-2016154434-A1 | SELECTIVE ALPHA-7 NICOTINIC RECEPTOR AGONISTS AND METHODS FOR MAKING AND USING THEM | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-09-29 | — | — | WO | disclosed |
| US-20150218192-A1 | Polysilylated Organosilane Compounds | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 2015-08-06 | — | — | US | disclosed |
| US-20150218192-A1 | Polysilylated Organosilane Compounds | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 2015-08-06 | — | — | US | disclosed |
| WO-2014006221-A1 | POLYSILYLATED ORGANOSILANE COMPOUNDS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S) (FR) | 2014-01-09 | — | — | WO | disclosed |
| EP-2657236-A1 | NOVEL 2-ALKYNYL-N9-PROPARGYLADENINE AND MEDICINAL USE THEREOF | YAMASA CORPORATION (JP) | 2013-10-30 | — | — | EP | disclosed |
| US-7626005-B2 | Inhibitors of aminoglycoside 6′-N-acetyltransferases, compositions and uses thereof | MCGILL UNIVERSITY (CA) | 2009-12-01 | — | — | US | disclosed |
| EP-1740587-A4 | SELECTIVE ANTAGONISTS OF A-2A- ADENOSINE RECEPTORS | ADENOSINE THERAPEUTICS LLC (US) | 2009-07-15 | — | — | EP | disclosed |
| EP-1740587-A2 | SELECTIVE ANTAGONISTS OF A-2A- ADENOSINE RECEPTORS | Adenosine Therapeutics, LLC (US) | 2007-01-10 | — | — | EP | disclosed |
| WO-2005097140-A2 | SELECTIVE ANTAGONISTS OF A2A ADENOSINE RECEPTORS | ADENOSINE THERAPEUTICS, LLC (US) | 2005-10-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150218192-A1 | Polysilylated Organosilane Compounds | ALG8, UGT1A9, SI | AHCY 3209/4885ADORA2A 4370/4885ADORA1 4554/4885 |
| US-10308638-B2 | Selective alpha-7 nicotinic receptor agonists and methods for making and using them | CHRNA7, CHRNA1, CHRNA5 | AHCY 2178/4885ADORA2A 186/4885ADORA1 52/4885 |
| US-20180244653-A1 | SELECTIVE ALPHA-7 NICOTINIC RECEPTOR AGONISTS AND METHODS FOR MAKING AND USING THEM | CHRNA7, CHRNA1, CHRNA5 | AHCY 2178/4885ADORA2A 186/4885ADORA1 52/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.