Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 7/20 | 0.35 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.35 |
| ▸ | HTR3B | O95264 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.35 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.35 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.30 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.30 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.30 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.30 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.30 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL169235 | 0.78 | MAPK8 (0.54) | MAPK8HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL31746758 | 0.78 | MAPK8 (0.54) | MAPK8HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL22717083 | 0.74 | ADORA2A (0.42) | IKBKBMAPK8HTR3EHTR3BHTR3A | |
| SCHEMBL24541113 | 0.69 | MAPK8 (0.57) | IKBKBMAPK8 | |
| SCHEMBL25823761 | 0.65 | IKBKB (0.38) | IKBKBMAPK8ADORA2AGRIA1 | |
| SCHEMBL24541135 | 0.65 | MAPK8 (0.47) | IKBKBMAPK8 | |
| SCHEMBL25299727 | 0.65 | ADORA2A (0.53) | MAPK8HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL22717201 | 0.60 | NUDT1 (0.32) | NUDT1 | |
| SCHEMBL20600558 | 0.59 | NUDT1 (0.38) | NUDT1ADORA2ATLR7GRIN2DGRIN3B | |
| SCHEMBL6599150 | 0.59 | TDP1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116888120-A | PRMTS inhibitors | 美国安进公司 | 2023-10-13 | — | — | CN | disclosed |