Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 7/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | CCR1 | P32246 | 3/20 | 0.43 |
| ▸ | S1PR2 | O95136 | 3/20 | 0.39 |
| ▸ | CCR3 | P51677 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29138884 | 1.00 | OPRL1 (0.48) | OPRL1OPRM1OPRK1OPRD1DRD2 | |
| SCHEMBL29138902 | 0.88 | OPRL1 (0.43) | OPRL1OPRM1OPRK1OPRD1DRD2 | |
| SCHEMBL13502008 | 0.83 | OPRM1 (0.49) | OPRL1OPRM1OPRK1OPRD1DRD2 | |
| SCHEMBL29138933 | 0.81 | MAOA (0.39) | OPRL1OPRM1OPRK1OPRD1THRB | |
| SCHEMBL28974070 | 0.77 | MAOA (0.41) | OPRL1OPRM1OPRK1OPRD1THRB | |
| SCHEMBL14748330 | 0.77 | OPRL1 (0.48) | OPRL1OPRM1OPRK1OPRD1DRD2 | |
| SCHEMBL23605148 | 0.75 | GRIN2B (0.47) | — | |
| SCHEMBL28796806 | 0.74 | OPRM1 (0.60) | OPRL1OPRM1OPRK1OPRD1DRD2 | |
| SCHEMBL10077966 | 0.73 | OPRL1 (0.57) | OPRL1OPRM1OPRK1OPRD1DRD2 | |
| SCHEMBL18282707 | 0.73 | OPRL1 (0.55) | OPRL1OPRM1OPRK1OPRD1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116888120-A | PRMTS inhibitors | 美国安进公司 | 2023-10-13 | — | — | CN | disclosed |