Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28974070 | 0.91 | MAOA (0.41) | MAOAMAOBKDM1AOPRL1OPRM1 | |
| SCHEMBL29138885 | 0.81 | OPRL1 (0.48) | OPRL1OPRM1OPRD1OPRK1THRB | |
| SCHEMBL29138884 | 0.81 | OPRL1 (0.48) | OPRL1OPRM1OPRD1OPRK1THRB | |
| SCHEMBL23993224 | 0.76 | MAOA (0.42) | MAOAMAOBKDM1AOPRL1OPRM1 | |
| SCHEMBL28818434 | 0.74 | HSD11B1 (0.41) | MAOAMAOBKDM1AOPRL1OPRM1 | |
| SCHEMBL29138902 | 0.73 | OPRL1 (0.43) | MAOAMAOBKDM1AOPRL1OPRM1 | |
| SCHEMBL25004297 | 0.73 | MAOA (0.42) | MAOAMAOBKDM1AOPRL1OPRM1 | |
| SCHEMBL21767866 | 0.68 | DRD3 (0.41) | MAOAMAOBKDM1A | |
| SCHEMBL17729499 | 0.67 | APP (0.43) | MAOAMAOBKDM1AOPRL1OPRM1 | |
| SCHEMBL31506631 | 0.67 | CNR1 (0.40) | OPRL1OPRM1HSD11B1MEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116888120-A | PRMTS inhibitors | 美国安进公司 | 2023-10-13 | — | — | CN | disclosed |