Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 5/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | CCR1 | P32246 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29138884 | 0.88 | OPRL1 (0.48) | OPRL1OPRM1OPRD1OPRK1DRD2 | |
| SCHEMBL29138885 | 0.88 | OPRL1 (0.48) | OPRL1OPRM1OPRD1OPRK1DRD2 | |
| SCHEMBL14302044 | 0.81 | OPRM1 (0.43) | OPRL1OPRM1OPRD1OPRK1DRD2 | |
| SCHEMBL23605148 | 0.80 | GRIN2B (0.47) | MAOAMAOBKDM1A | |
| SCHEMBL24397903 | 0.77 | OPRL1 (0.46) | OPRL1OPRM1OPRD1OPRK1DRD2 | |
| SCHEMBL17729514 | 0.77 | OPRL1 (0.43) | OPRL1OPRM1OPRD1OPRK1DRD2 | |
| SCHEMBL11605946 | 0.74 | HPGD (0.50) | OPRL1OPRM1OPRD1OPRK1MEN1 | |
| SCHEMBL18282707 | 0.74 | OPRL1 (0.55) | OPRL1OPRM1OPRD1OPRK1DRD2 | |
| SCHEMBL29138933 | 0.73 | MAOA (0.39) | OPRL1OPRM1OPRD1OPRK1MAOA | |
| SCHEMBL28974070 | 0.72 | MAOA (0.41) | OPRL1OPRM1OPRD1OPRK1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116888120-A | PRMTS inhibitors | 美国安进公司 | 2023-10-13 | — | — | CN | disclosed |