SCHEMBL29138904

SCHEMBL29138904

Cc1n[nH]c2c1c(N)nc1cc[c]cc12

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24541229 0.71 TDP1 (0.47) GAAKMT2A
SCHEMBL8486872 0.68 HSD17B10 (0.39) GAAKMT2A
SCHEMBL29761649 0.68 ILK (0.47) GAAKMT2A
SCHEMBL24540936 0.67 HCAR2 (0.35) KMT2A
SCHEMBL1694765 0.64 CYP1A2 (0.43) GAA
SCHEMBL3820902 0.64 DCPS (0.53)
SCHEMBL6320460 0.64 NCF1 (0.58) KMT2A
SCHEMBL29138790 0.64 PI4KA (0.34)
SCHEMBL478887 0.63 PDPK1 (0.54) GAA
SCHEMBL1230771 0.62 CYP1A2 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116888120-A PRMTS inhibitors 美国安进公司 2023-10-13 CN disclosed