Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 2/20 | 0.34 |
| ▸ | CASP1 | P29466 | 2/20 | 0.34 |
| ▸ | CASP7 | P55210 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | RAD52 | P43351 | 2/20 | 0.34 |
| ▸ | GPR3 | P46089 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3820902 | 0.73 | DCPS (0.53) | — | |
| SCHEMBL6320460 | 0.73 | NCF1 (0.58) | HSD17B10ALDH1A1CYP1A2KDM4EKMT2A | |
| SCHEMBL27296318 | 0.72 | ALDH1A1 (0.64) | HSD17B10ALDH1A1HPGDCYP1A2NUDT1 | |
| SCHEMBL30025532 | 0.72 | ALDH1A1 (0.64) | HSD17B10ALDH1A1HPGDCYP1A2NUDT1 | |
| SCHEMBL194246 | 0.71 | MAPT (0.39) | HSD17B10ALDH1A1CYP1A2MAPTKDM4E | |
| SCHEMBL1857081 | 0.69 | ACHE (0.49) | HSD17B10ALDH1A1HPGDCYP1A2NUDT1 | |
| SCHEMBL29138904 | 0.68 | GAA (0.33) | KMT2AGAA | |
| SCHEMBL8707994 | 0.68 | MAOA (0.31) | MAPTMAOA | |
| SCHEMBL28042218 | 0.67 | ALDH1A1 (0.62) | HSD17B10ALDH1A1HPGDCYP1A2NUDT1 | |
| SCHEMBL8707262 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999001442-A1 | TRIAZINE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | ZENECA LIMITED (GB) | 1999-01-14 | — | — | WO | claimed |
| WO-1999001442-A1 | TRIAZINE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | ZENECA LIMITED (GB) | 1999-01-14 | — | — | WO | disclosed |