SCHEMBL29138928

SCHEMBL29138928

CCCC[Sn](CCCC)(CCCC)COCC(C)N

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.37
TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31238954 1.00 OPRM1 (0.37) OPRM1TP53
SCHEMBL3146855 0.83 L3MBTL1 (0.31)
SCHEMBL21491148 0.81 HTT (0.33)
SCHEMBL22499411 0.79
SCHEMBL22499314 0.79
SCHEMBL22499312 0.79
SCHEMBL4881159 0.78 TSHR (0.33)
SCHEMBL29920164 0.74
SCHEMBL509694 0.73 LMNA (0.30)
SCHEMBL6697084 0.72 ALDH1A1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119053603-A Nitrogen-containing tri-condensed ring PRMT5 inhibitor, preparation method and pharmaceutical application thereof 上海和誉生物医药科技有限公司 2024-11-29 CN disclosed
CN-118946566-A Heterocyclic compounds as ubiquitin-specific protease 7 inhibitors 阿尔麦克探索有限公司 2024-11-12 CN disclosed
CN-116888120-A PRMTS inhibitors 美国安进公司 2023-10-13 CN disclosed