Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PNMT | P11086 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29138905 | 1.00 | LMNA (0.36) | LMNAKDM4EALDH1A1HCRTR1HCRTR2 | |
| SCHEMBL29138899 | 0.82 | LRRK2 (0.39) | HCRTR1HCRTR2EPHX2 | |
| SCHEMBL29138851 | 0.82 | LRRK2 (0.39) | HCRTR1HCRTR2EPHX2 | |
| SCHEMBL29138918 | 0.80 | AKR1C3 (0.39) | LMNAKDM4EALDH1A1SMN1; SMN2PDE2A | |
| SCHEMBL29138870 | 0.80 | AKR1C3 (0.39) | LMNAKDM4EALDH1A1SMN1; SMN2PDE2A | |
| SCHEMBL29138796 | 0.80 | AKR1C3 (0.39) | LMNAKDM4EALDH1A1SMN1; SMN2PDE2A | |
| SCHEMBL29138900 | 0.75 | HIF1A (0.39) | LMNAKDM4ECYP3A4SMN1; SMN2GAA | |
| SCHEMBL29138891 | 0.75 | AR (0.36) | ALDH1A1EPHX2HDAC8HDAC6 | |
| SCHEMBL29138864 | 0.75 | AR (0.36) | ALDH1A1EPHX2HDAC8HDAC6 | |
| SCHEMBL29138869 | 0.75 | HIF1A (0.39) | LMNAKDM4ECYP3A4SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116888120-A | PRMTS inhibitors | 美国安进公司 | 2023-10-13 | — | — | CN | disclosed |